Results 61 to 70 of about 2,605 (196)

Safety of levocetirizine treatment in young atopic children: an 18-month an 18-month study.

open access: yes, 2007
There are more than 40 H-1-antihistamines available worldwide. Most of these medications have never been optimally studied in prospective, randomized, double-masked, placebo-controlled trials in children.
EPAAC Study Group: . . . M. Masi   +6 more
core   +1 more source

Evaluation of analgesic and anti-inflammatory activity of Levocetirizine in albino rats [PDF]

open access: yes, 2019
Background: Levocetirizine, the R-enantiomer of Cetirizine has pharmacokinetically and pharmacodynamically favourable characteristics, with rapid onset of action, high bioavailability, high affinity for and occupancy of the H1-receptor, limited ...
Jaju, Jugalkishor B.   +3 more
core   +1 more source

RECOVER Guidelines: First Aid. Evidence, Treatment Recommendations, Knowledge Gap Analysis, and Clinical Guidelines for Acute Allergy and Anaphylaxis in Dogs and Cats

open access: yesJournal of Veterinary Emergency and Critical Care, Volume 36, Issue S1, Page S63-S89, August 2026.
ABSTRACT Objective To systematically evaluate relevant evidence, devise and present treatment recommendations, and identify and present critical knowledge gaps regarding treatment of uncomplicated allergic reaction and anaphylaxis in dogs and cats. Design Standardized, systematic evaluation of literature pertinent to uncomplicated allergic reaction and
Jamie M. Burkitt‐Creedon   +16 more
wiley   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2230-2238, July 2026.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi   +3 more
wiley   +1 more source

Experience of Using Levocetirizine in Pediatric Practice

open access: yes, 2014
The paper represents the latest views on antihistamine drugs use in pediatrics. For today, the most essential issue at acute and chronic allergic diseases in children is the use of new antihistamine drug ...
Yu.V. Marushko
core   +1 more source

The role of histamine H 1 receptors in the complex treatment of patients with allergic rhinitis

open access: yesМедицинский совет, 2019
In the article the actual problem of modern medicine – treatment of patients with allergic rhinitis (AR). Given the prevalence of AR are discussed classification issues, the etiology and pathogenesis of the disease.
S. V. Starostina   +2 more
doaj   +1 more source

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part II—Guidelines on Oral and Ocular Treatments

open access: yesAllergy, Volume 81, Issue 6, Page 1947-1970, June 2026.
ABSTRACT Background Oral and ocular medications are frequently used in the treatment of allergic rhinitis (AR). As part of the update of the Allergic Rhinitis and its Impact on Asthma (ARIA)‐EAACI guidelines, this manuscript presents the ARIA‐EAACI 2024–2025 recommendations for oral and ocular treatments.
Rafael José Vieira   +230 more
wiley   +1 more source

Availability and Costs of Allergic Rhinitis Treatments Across the World: A Survey of ARIA Experts

open access: yesAllergy, Volume 81, Issue 6, Page 2069-2078, June 2026.
We surveyed experts of the ARIA group on the costs of medications for allergic rhinitis in the respective countries. Overall, oral antihistamines are the cheapest medications while fixed combinations of antihistamines + corticosteroids are the most expensive.
Maria Clara Urbano   +75 more
wiley   +1 more source

Machine Learning‐Based Prediction of Drug‐Induced QTc Changes in a Large Finnish Biobank Cohort

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT Prolongation of the QT interval is a known precursor to serious arrhythmias and sudden cardiac death, often triggered by medication use. Current medication risk evaluation platforms rely on literature‐based synthesis and may lag behind real‐world developments.
Ville Langén   +7 more
wiley   +1 more source

A treatment for allergic rhinitis: a view on the role of levocetirizine

open access: yes, 2005
Background: Allergic rhinitis is a significant public health concern in many developed countries. However, despite evidence for a significant impact on patients' quality of life (QoL) including sleep disruption and reduced daytime performance, allergic ...
Holgate, Stephen   +3 more
core   +1 more source

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