Results 271 to 280 of about 74,631 (338)

Reply to "Reconsidering dopaminergic modulation in Alzheimer's disease: A case for levodopa/carbidopa as a disease-modifying agent". [PDF]

Alzheimers Dement
Sárkány Z, Damásio J, Macedo-Ribeiro S, Martins PM.   +3 more
europepmc   +1 more source

Deep Learning to Differentiate Parkinsonian Syndromes Using Multimodal Magnetic Resonance Imaging: A Proof‐of‐Concept Study

Movement Disorders, EarlyView.
Abstract Background The differentiation between multiple system atrophy (MSA) and Parkinson's disease (PD) based on clinical diagnostic criteria can be challenging, especially at an early stage. Leveraging deep learning methods and magnetic resonance imaging (MRI) data has shown great potential in aiding automatic diagnosis.
Giulia Maria Mattia, Lydia Chougar, Alexandra Foubert‐Samier, Wassilios G. Meissner, Margherita Fabbri, Anne Pavy‐Le Traon, Olivier Rascol, David Grabli, Bertrand Degos, Nadya Pyatigorskaya, Alice Faucher, Marie Vidailhet, Jean‐Christophe Corvol, Stéphane Lehéricy, Patrice Péran   +14 more
wiley   +1 more source

Modulatory effect of levodopa on the basal ganglia-cerebellum connectivity in Parkinson's disease. [PDF]

NPJ Parkinsons Dis
Yun JJ, Abulikemu S, Jangwanich KL, Tai YF, Haar S.   +4 more
europepmc   +1 more source

Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Inhibition of Nod‐like receptor protein 3 (NLRP3) inflammasome within the central nervous system (CNS) is a promising therapeutic target for the treatment of Parkinson's disease (PD). Objectives This phase 1b open‐label study was conducted in elderly healthy volunteers (HV) and PD patients.
Nicholas Clarke, Peter Thornton, Valérie Reader, Nicola Lindsay, Zsofia Digby, Bianca Mullen, Michelle Gorman, Eric Jacobson, Grant Langdon, Hilary Johnstone, Alistair Wheeler, Alan P. Watt   +11 more
wiley   +1 more source

The effect of peripheral dopamine on fracture healing: an experimental study in a rat model. [PDF]

J Orthop Surg Res
Yücel MO, Dalaslan RE, Sağlam S, Arıcan M, Karaduman ZO, Turhan B, Demir F.   +6 more
europepmc   +1 more source

Screening of Hidden Pathogenic Structural Variants in PRKN

Movement Disorders, EarlyView.
Kensuke Daida, Guillaume Cogan, Christelle Tesson, Suzanne Lesage, Susen Schaake, Alexander Balck, Joanne Trinh, Katja Lohmann, Laksh Malik, Breeana Baker, Kimberly Paquette, Abraham Moller, Carolyn Sue, Manabu Funayama, Nobutaka Hattori, Andrew Singleton, Christine Klein, Alexis Brice, Kimberley J. Billingsley, Cornelis Blauwendraat   +19 more
wiley   +1 more source

Deep Brain Stimulation in Children and Adolescents with ε‐Sarcoglycan Myoclonus Dystonia Causes a Sustained Improvement in Motor Functionality and Quality of Life

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation of the globus pallidus internus (DBS‐GPi) has shown efficacy in adult patients with SGCE‐related myoclonus dystonia. However, evidence regarding its impact in pediatric populations is limited. Objectives The aim was to evaluate motor and non‐motor outcomes following DBS‐GPi intervention in children and ...
Ainara Salazar‐Villacorta, Ana Cazurro‐Gutiérrez, Lucy Dougherty‐de Miguel, Julia Ferrero‐Turrión, Anna Marcé‐Grau, Marta Folch‐Benito, Álvaro Lucero‐Garófano, Alfons Macaya, Antonio Moreno‐Galdó, Maria I. Vanegas, Marta Correa‐Vela, María Victoria González, Gemma Español‐Martín, Martha Loredo, Ignacio Delgado, Esther Toro‐Tamargo, Margarita Figueroa, Dolores Vilas, Manel Tardáguila, Jorge Muñoz, Lourdes Ispierto, Ramiro Álvarez, Agustí Bescós, Belén Pérez‐Dueñas   +23 more
wiley   +1 more source

Inefficacy of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease Patients with Levodopa-Induced Dyskinesias: Results from a Pilot Study. [PDF]

Biomedicines
Medrano-Hernández A, Neri-Nani G, Rodríguez-Violante M, Drucker-Colín R, Chavarría A.   +4 more
europepmc   +1 more source

Demographic and Clinical Profiles of Parkinson's Disease in India: Observations from a Nation‐Wide Multicenter Study

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) phenotype may vary with genetic, ethno‐geographic, cultural, and environmental factors. Objectives The aim was to develop a clinical database of PD in India and assess the influence of age‐at‐onset (AAO), gender, and motor subtype on the clinical profile of PD.
Asha Kishore, Rupam Borgohain, Divya Kalikavil Puthenveedu, Roopa Rajan, Pramod Kumar Pal, Rukmini‐Mridula Kandadai, Ravi Yadav, Sahil Mehta, Hrishikesh Kumar, Niraj Kumar, Prashanth Lingappa Kukkle, Soaham Desai, Kuldeep Shetty, Pettarusp Wadia, Annu Aggarwal, Pankaj Ashok Agarwal, Mirza Masoom Abbas, Syam Krishnan, Divya Madathiparambil Radhakrishnan, Gurusidheswar Mahadevappa Wali, Achal Srivastava, Nitish Kamble, Teresa Maria D′ Costa Ferreira, Vivek Lal, Ashwin Ashok Kumar Sreelatha, Luis‐Giraldo Gonzalez‐Ricardo, Manas Chacko, Manu Sharma   +27 more
wiley   +1 more source

Levodopa treatment: impacts and mechanisms throughout Parkinson's disease progression. [PDF]

J Neural Transm (Vienna)
Riederer P, Strobel S, Nagatsu T, Watanabe H, Chen X, Löschmann PA, Sian-Hulsmann J, Jost WH, Müller T, Dijkstra JM, Monoranu CM.   +10 more
europepmc   +1 more source