Semaglutide therapy and iatrogenic thyrotoxicosis [PDF]
Levothyroxine is the backbone of hypothyroidism treatment. The dosage of levothyroxine varies; however, as an estimate, an average adult patient will require 1.6 micrograms per kilogram of body weight. We present the case of a patient with hypothyroidism,
Maxim John Levy Barnett+2 more
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The relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients: a large retrospective study [PDF]
Objective: This study examined the relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients. The aim was to ascertain whether elevated free thyroxine in treated patients suggests overmedication or is essential for ...
Toshihiko Kasahara
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Levothyroxine therapy in thyroidectomized patients: ongoing challenges and controversies [PDF]
This mini-review provides an update on the challenges and controversies surrounding levothyroxine therapy in thyroidectomized patients, following an extensive review on dosing strategies and available formulations.
Leonardo Rossi+4 more
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Association between levothyroxine supplementation for hypothyroidism in late pregnancy and risk of prematurity: a population-based cohort study [PDF]
Background Hypothyroidism in pregnancy is associated with obstetrical and fetal complications, such as prematurity. However, whether its management by levothyroxine affects the risk of prematurity is not yet clear.
Maya Laham, Odile Sheehy, Anick Bérard
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Phase 1 Study Evaluating the Pharmacokinetics, Dose Proportionality, Bioavailability, and Tolerability of Subcutaneous Levothyroxine Sodium (XP‐8121) [PDF]
Levothyroxine sodium has been the cornerstone of hypothyroidism management worldwide, with daily oral administration (PO) recognized as standard of care.
Richard Fitch+4 more
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Levothyroxine tablet has been used for improving serum thyroid hormones. Despite its efficacy, there has been a persistent recurrence. We aimed to evaluate the efficacy of levothyroxine regimen (administered as sodium tablets or liquid) therapy ...
Dingji Hao+6 more
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Background For the treatment of hypothyroidism, patients are usually placed on lifelong levothyroxine replacement therapy. Achieving clinical and biochemical euthyroid status is sometimes difficult because of several factors, including poor compliance or
Zareen Kiran+4 more
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Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy [PDF]
Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function.
Youngha Choi+7 more
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Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured
Yi Jiang Chua+4 more
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Suicide attempt of an overt hypothyroid patient with levothyroxine: A case report
Rationale: Levothyroxine is the most commonly used agent in thyroid hormone replacement therapy. Although there are many hypothyroid patients who use levothyroxine as a treatment, high level of thyroid stimulating hormone is found in a limited number of ...
Ayse Sahin Tutak
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