Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions [PDF]
AAPS Open, 2022 Introduction Levothyroxine, the standard-of-care treatment for hypothyroidism, is susceptible to degradation when exposed to light and moisture and is an FDA-designated narrow therapeutic index drug. In this report, we examined how different packaging (e.
Jonathan Chun
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Apalutamide treatment and refractory hypothyroidism: effects of apalutamide on levothyroxine metabolism [PDF]
European Thyroid JournalApalutamide, a selective androgen receptor antagonist, is a new treatment for prostate cancer. Among the side effects observed during apalutamide treatment, an increased risk of hypothyroidism has been reported, particularly in patients previously ...
Florie Quattrochi +2 more
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Levothyroxine supplementation after hemithyroidectomy in patients with low-risk differentiated thyroid cancer: risk factors and withdrawal strategy [PDF]
Frontiers in EndocrinologyBackgroundThe American Thyroid Association guidelines recommend maintaining thyroid-stimulating hormone (TSH) levels < 2 mIU/L postoperatively in low-risk patients. Patients with low-risk differentiated thyroid cancer, defined as intrathyroidal tumors
Jin Seok Lee +4 more
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Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis [PDF]
Case Reports in Endocrinology, 2015 An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor. On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable.
Peter N. Taylor +8 more
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From Resistance to Relief: IV Levothyroxine in Refractory Hypothyroidism Management [PDF]
Clinical Case ReportsThis case report details the clinical scenario of a 27‐year‐old female patient diagnosed with idiopathic refractory hypothyroidism. Despite adherence to prescribed oral levothyroxine therapy, she continued to experience persistent symptoms such as ...
Mohammad Amro +6 more
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Semaglutide therapy and iatrogenic thyrotoxicosis [PDF]
Endocrinology, Diabetes & Metabolism Case ReportsLevothyroxine is the backbone of hypothyroidism treatment. The dosage of levothyroxine varies; however, as an estimate, an average adult patient will require 1.6 micrograms per kilogram of body weight. We present the case of a patient with hypothyroidism,
Maxim John Levy Barnett +2 more
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A Combination of L-Triiodothyronine and Levothyroxine in the Treatment of Tyrosine Kinase Inhibitor-Induced Hypothyroidism in Renal Cell Carcinoma: A Case Report. [PDF]
Clin Case RepHan YJ, Chen S, Miao R, Yu ZY, Wang YB.
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European Journal of Translational Myology, 2023 Levothyroxine tablet has been used for improving serum thyroid hormones. Despite its efficacy, there has been a persistent recurrence. We aimed to evaluate the efficacy of levothyroxine regimen (administered as sodium tablets or liquid) therapy ...
Dingji Hao +6 more
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Journal of Medical Case Reports, 2023 Background For the treatment of hypothyroidism, patients are usually placed on lifelong levothyroxine replacement therapy. Achieving clinical and biochemical euthyroid status is sometimes difficult because of several factors, including poor compliance or
Zareen Kiran +4 more
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Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function.
Youngha Choi +7 more
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