Results 1 to 10 of about 25,504 (178)

Stability of levothyroxine tablets in blister packaging versus bottles and vials under simulated in-use conditions [PDF]

AAPS Open, 2022
Introduction Levothyroxine, the standard-of-care treatment for hypothyroidism, is susceptible to degradation when exposed to light and moisture and is an FDA-designated narrow therapeutic index drug. In this report, we examined how different packaging (e.
Jonathan Chun
doaj   +2 more sources

Apalutamide treatment and refractory hypothyroidism: effects of apalutamide on levothyroxine metabolism [PDF]

European Thyroid Journal
Apalutamide, a selective androgen receptor antagonist, is a new treatment for prostate cancer. Among the side effects observed during apalutamide treatment, an increased risk of hypothyroidism has been reported, particularly in patients previously ...
Florie Quattrochi, Solange Grunenwald, Philippe Caron   +2 more
doaj   +2 more sources

Levothyroxine supplementation after hemithyroidectomy in patients with low-risk differentiated thyroid cancer: risk factors and withdrawal strategy [PDF]

Frontiers in Endocrinology
BackgroundThe American Thyroid Association guidelines recommend maintaining thyroid-stimulating hormone (TSH) levels < 2 mIU/L postoperatively in low-risk patients. Patients with low-risk differentiated thyroid cancer, defined as intrathyroidal tumors
Jin Seok Lee, Eun Ju Ha, Ho Jung Jeong, Soo Young Kim, Hyeung Kyoo Kim   +4 more
doaj   +2 more sources

Efficacy and safety of postoperative levothyroxine sodium tablets for improving serum thyroid hormone levels and tumor marker levels in patients with thyroid tumors

European Journal of Translational Myology, 2023
Levothyroxine tablet has been used for improving serum thyroid hormones. Despite its efficacy, there has been a persistent recurrence. We aimed to evaluate the efficacy of levothyroxine regimen (administered as sodium tablets or liquid) therapy ...
Dingji Hao, Linxiao Tian, Haoting He, Congru Zhu, Lili Guo, Keao Zhang, Jie Zhang   +6 more
doaj   +1 more source

Levothyroxine absorption test followed by directly observed treatment on an outpatient basis to address long-term high thyrotropin levels in a hypothyroid patient: a case report

Journal of Medical Case Reports, 2023
Background For the treatment of hypothyroidism, patients are usually placed on lifelong levothyroxine replacement therapy. Achieving clinical and biochemical euthyroid status is sometimes difficult because of several factors, including poor compliance or
Zareen Kiran, Khalilullah Shabbir Shaikh, Nazish Fatima, Namra Tariq, Akhtar Ali Baloch   +4 more
doaj   +1 more source

Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function.
Youngha Choi, Se Yong Jung, Jung Min Park, Junghwan Suh, Eun Jung Shin, Hyun Wook Chae, Ho-Seong Kim, Ahreum Kwon   +7 more
doaj   +1 more source

Successful Oral Levothyroxine Desensitization in a Patient with Severe Hypothyroidism Post Radioactive Iodine Therapy

Journal of the ASEAN Federation of Endocrine Societies, 2022
Levothyroxine remains the standard therapy for patients with hypothyroidism worldwide. Levothyroxine allergy is rarely seen and alternative therapies are less efficacious and scarcely available. The use of liothyronine (LT3) monotherapy is less favoured
Yi Jiang Chua, Bay Shing Shen, Taye Zhi Yun, Carolina Singarayar, Foo Siew Hui   +4 more
doaj   +1 more source

Suicide attempt of an overt hypothyroid patient with levothyroxine: A case report

Journal of Acute Disease, 2020
Rationale: Levothyroxine is the most commonly used agent in thyroid hormone replacement therapy. Although there are many hypothyroid patients who use levothyroxine as a treatment, high level of thyroid stimulating hormone is found in a limited number of ...
Ayse Sahin Tutak
doaj   +1 more source

Levothyroxine Timing during Ramadan: A Randomized Clinical Trial

International Journal of Endocrinology, 2023
Introduction. Hypothyroidism requires lifelong thyroid hormone replacement with levothyroxine. For most hypothyroid patients fasting during Ramadan, compliance with the administration procedure is a challenge.
Moeber Mahzari, Fahad Al Remthi, Ibrahim Ajwah, Mohammed Al Hazmi, Wesam Moafa, Awad Al Shahrani, Sameerah Al Shehri, Motasim Badri   +7 more
doaj   +1 more source

Prevalence and factors associated with chronic use of levothyroxine: A cohort study.

PLoS ONE, 2021
ImportanceLevothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use.ObjectiveTo assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with ...
Camilla Janett-Pellegri, Lea Wildisen, Martin Feller, Cinzia Del Giovane, Elisavet Moutzouri, Oliver Grolimund, Patrick Walter, Gérard Waeber, Pedro Marques-Vidal, Peter Vollenweider, Nicolas Rodondi   +10 more
doaj   +1 more source