Results 101 to 110 of about 36,523 (215)

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

A Report of the Mayo Clinic Experience on the Levothyroxine Absorption Test [PDF]

, 2020
Bernadette Biondi
openalex   +1 more source

Effectiveness of Bariatric Surgery for Improving Thyroid Function and Reducing Levothyroxine Dose in Patients With Obesity and Overt Hypothyroidism [PDF]

, 2023
Hanan H Alfaifi, Manar A Altowairqi, Rawan G Algethami, Atheer Hammad Altowairqi, Hajar D Althomali, Owaid M. Almalki   +5 more
openalex   +1 more source

Sleep Architecture Alterations Following High‐Dose Steroid Pulse Therapy: A Pilot Study Using a Portable Electroencephalogram‐Based Device

Neuropsychopharmacology Reports, Volume 45, Issue 4, December 2025.
High‐dose steroid pulse therapy markedly reduces total sleep time, REM, and NREM sleep, as objectively demonstrated for the first time using a portable EEG‐based device. ABSTRACT Background Sleep disturbance is a common side effect of high‐dose steroid pulse therapy (SPT).
Hiroki Endo, Yuki Shigetsura, Misaki Chahara, Keisuke Kido, Etsuro Nakanishi, Sakiho Ueda, Kimitoshi Kimura, Akira Kuzuya, Hirotsugu Kawashima, Riki Matsumoto, Masahiro Tsuda, Shunsaku Nakagawa, Tomohiro Terada   +12 more
wiley   +1 more source

The relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients: a large retrospective study

European Thyroid Journal
Objective: This study examined the relationship between levothyroxine dosage and free thyroxine levels in hypothyroid patients. The aim was to ascertain whether elevated free thyroxine in treated patients suggests overmedication or is essential for ...
Toshihiko Kasahara
doaj   +1 more source

Risk of Subsequent Primary Cancers in Thyroid Cancer Survivors according to the Dose of Levothyroxine: A Nationwide Cohort Study [PDF]

Endocrinology and Metabolism
Background Current research has not investigated the effect of thyroid-stimulating hormone suppression therapy with levothyroxine on the risk for developing subsequent primary cancers (SPCs).
Min-Su Kim, Jang Won Lee, Min Kyung Hyun, Young Shin Song   +3 more
doaj   +1 more source

The safety of levothyroxine use with respect to bone mineral density [PDF]

, 2023
Tareq Moh'd Hussein Aljbouri, Suhair Shaher Tarawneh, Mohammad Jamil Ahmed Alabbadi, Yasmeen Ayoub Marzoq Al-Khawaldeh, Samer Mahmoud Mohammad Ali Alboun   +4 more
openalex   +1 more source

Near‐infrared fluorescence imaging with indocyanine green to identify parathyroid glands in two dogs undergoing bilateral modified intracapsular thyroidectomy

Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.
Abstract This case report describes one dog that underwent bilateral thyroidectomy and another that underwent unilateral thyroidectomy using near‐infrared fluorescence imaging with indocyanine green to visualise the external parathyroid glands to aid in their preservation.
Christine J. Ruffin, Brittany A. Carson, Mary A. McLoughlin, Laura E. Selmic   +3 more
wiley   +1 more source

Levothyroxine versus Levothyroxine with Iodine in Reduction of Thyroid Nodule Volume: A Double-Blind Randomized Controlled Trial

Philippine Journal of Otolaryngology Head and Neck Surgery, 2019
Objective: To compare levothyroxine alone and in combination with iodine on thyroid nodule volume reduction. Methods:           Design:           Double-Blind Randomized Controlled Trial           Setting:           Tertiary Government ...
Donnie Jan D. Segocio, Joseph E. Cachuela   +1 more
doaj   +1 more source

Levothyroxine Dose Adjustment to Optimise Therapy Throughout a Patient’s Lifetime

Advances in Therapy, 2019
Levothyroxine is the standard therapy for patients with hypothyroidism, a condition that affects up to 5% of people worldwide. While levothyroxine therapy has substantially improved the lives of millions of hypothyroid patients since its introduction in ...
L. Duntas, J. Jonklaas
semanticscholar   +1 more source