Results 101 to 110 of about 37,295 (269)

Thyroid screening in early pregnancy: Pros and cons [PDF]

, 2018
Universal thyroid screening in pregnancy is a key debate in thyroidology and obstetrics. It is well-established that thyroid hormones are essential for maintaining pregnancy and optimal fetal development.
John H. Lazarus, Kalyani Nagarahaj, Onyebuchi Okosieme, Onyebuchi Okosieme, Peter N. Taylor, Stamatios Zouras, Thinzar Min   +6 more
core   +3 more sources

Glycine N‐Acyltransferase Deficiency due to a Homozygous Nonsense Variant in the GLYAT: A Novel Inborn Error of Metabolism

JIMD Reports, Volume 66, Issue 5, September 2025.
ABSTRACT The enzyme glycine N‐acyltransferase (GLYAT) plays a crucial role in detoxifying both xenobiotic and endogenous compounds that contain a carboxylic acid group, such as benzoic acid. Data on the impact of human GLYAT on the glycine conjugation pathway is limited and difficult to determine.
Mona Nourbakhsh, Mohammad Miryounesi, Ali Tale, Parvaneh Karimzadeh, Hossein Sadeghi, Mohammad‐Reza Ghasemi, Nasrin Alipour, Elham Pourbakhtyaran, Nakisa Hooman, Maryam Razzaghy‐Azar, Mitra Nourbakhsh, Lil Klaas, Daniel Schulke, Jörn Oliver Sass   +13 more
wiley   +1 more source

Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]

, 2013
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core  

Virtual bioequivalence for achlorhydric subjects: The use of PBPK modelling to assess the formulation-dependent effect of achlorhydria [PDF]

, 2017
Majority of bioequivalence studies are conducted in healthy volunteers. It has been argued that bioequivalence may not necessarily hold true in relevant patient populations due to a variety of reasons which affect one formulation more than the other for ...
Darwich Adam S., Doki Kosuke, Patel Nikunjkumar, Rostami-Hodjegan Amin, 土岐 浩介   +4 more
core   +1 more source

British Thyroid Association Survey of Graves' Disease Management in the UK

Clinical Endocrinology, Volume 103, Issue 3, Page 376-384, September 2025.
ABSTRACT Background Recent years have seen changes and uncertainties in evidence and guideline recommendations in Graves' disease treatment. To understand the impact of these developments on current practice, we undertook a survey of Graves' disease management in the United Kingdom and compared this to other national and international surveys.
Michael Atkinson, Medha Agrawal, Koteshwara Muralidhara, Prakash Abraham, Bijay Vaidya, Onyebuchi E. Okosieme   +5 more
wiley   +1 more source

Levothyroxine versus Levothyroxine with Iodine in Reduction of Thyroid Nodule Volume: A Double-Blind Randomized Controlled Trial

Philippine Journal of Otolaryngology Head and Neck Surgery, 2019
Objective: To compare levothyroxine alone and in combination with iodine on thyroid nodule volume reduction. Methods:           Design:           Double-Blind Randomized Controlled Trial           Setting:           Tertiary Government ...
Donnie Jan D. Segocio, Joseph E. Cachuela   +1 more
doaj   +1 more source

Association of coeliac disease and thyroid disorders [PDF]

, 2008
A case study is presented. This involves a woman who presented with features of hyperthyroidism, which were refractory to conventional therapy. She was eventually diagnosed to have co-existing coeliac disease and eventually improved on a diet excluding ...
Sciberras, Robert
core  

Reversible normalisation of serum TSH levels in patients with autoimmune atrophic gastritis who received L-T4 in tablet form after switching to an oral liquid formulation: A case series [PDF]

, 2016
Background: L-thyroxine (L-T4) malabsorption is a potential concern in patients with autoimmune atrophic gastritis. Methods: We evaluated five patients with autoimmune gastritis, who showed high serum thyrotropin (TSH) levels (in the hypothyroid range ...
ANTONELLI, ALESSANDRO, Fallahi, Poupak, Ferrari, Silvia Martina, Ruffilli, Ilaria   +3 more
core   +1 more source

The Use of miRNA Panel as a Growth Plate Marker of Short‐Term Response to GH

Clinical Endocrinology, Volume 103, Issue 3, Page 327-337, September 2025.
ABSTRACT Introduction Recombinant human growth hormone (GH) therapy shows variable growth responses in patients with growth hormone deficiency (GHD), highlighting the need for reliable biomarkers to predict individual sensitivity. Objective This study investigated circulating microRNAs (miRNAs) involved in growth plate regulation during GH therapy in ...
Caroline Rosa Pellicciari, Thayna Rosa Bispo, Itatiana Ferreira Rodart, Leandra Steinmetz, Adriana Aparecida Siviero Miachon, Angela Maria Spinola e Castro, Durval Damiani, Cristiane Kochi, Carlos Alberto Longui   +8 more
wiley   +1 more source

Levothyroxine improves Paraoxonase (PON-1) serum levels in patients with primary hypothyroidism: Case–control study

Journal of Advanced Pharmaceutical Technology & Research, 2018
Primary hypothyroidism is associated with oxidative stress and insufficient antioxidant capacity. This study was conducted to evaluate the effects of levothyroxine replacement therapy on paraoxonase 1 (PON-1) serum levels in a patients with primary ...
Marwa S Al-Naimi, Nawar R Hussien, Huda A Rasheed, Hayder M Al-kuraishy, Ali I Al-Gareeb   +4 more
doaj   +1 more source