Results 11 to 20 of about 37,295 (269)
Levothyroxine Therapy in Thyrodectomized Patients [PDF]
Frontiers in Endocrinology, 2021 Administration of the optimal dose of levothyroxine (LT4) is crucial to restore euthyroidism after total thyroidectomy. An insufficient or excessive dosage may result in hypothyroidism or thyrotoxicosis, either one associated with a number of symptoms ...
Paolo Miccoli +2 more
doaj +4 more sources
Bioequivalence studies for levothyroxine [PDF]
The AAPS Journal, 2005 The Food and Drug Administration (FDA) Guidance for Bioavailability and Bioequivalence Studies for Levothyroxine has been challenged by companies that manufacture brand-name products. Their contention is that the current guidance does not adequately address the endogenous background levels of the drug, and that the ratios of the PK parameters, a basis ...
Sanford Bolton
openalex +5 more sources
Thyroxine treatment with softgel capsule formulation. Usefulness in hypothyroid patients without malabsorption [PDF]
, 2018 Background: Levothyroxine sodium (LT4) is the therapy of choice for hypothyroidism. In the last decade, new LT4 formulations, such as liquid and softgel capsules, became available. Even if some evidence has been reached in the efficacy of liquid LT4 in
Centanni, Marco +3 more
core +6 more sources
Pseudomalabsorption of Levothyroxine. A Case Report.
Endocrine Journal, 2000 A 51-year-old woman who had been treated with levothyroxine sodium because of hypothyroidism after total thyroidectomy for thyroidal cancer was admitted to our hospital for persistent hypothyroidism despite large dose administration of levothyroxine (600 microg/day). The patient complained of severe general fatigue and body weight gain. Free thyroxine,
Daisuke Ogawa +7 more
openalex +5 more sources
Levothyroxine Timing during Ramadan: A Randomized Clinical Trial
International Journal of Endocrinology, 2023 Introduction. Hypothyroidism requires lifelong thyroid hormone replacement with levothyroxine. For most hypothyroid patients fasting during Ramadan, compliance with the administration procedure is a challenge.
Moeber Mahzari +7 more
doaj +1 more source
Prevalence and factors associated with chronic use of levothyroxine: A cohort study.
PLoS ONE, 2021 ImportanceLevothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use.ObjectiveTo assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with ...
Camilla Janett-Pellegri +10 more
doaj +1 more source
مجله كليه طب الكندي, 2023 Background: Hypothyroidism is the most abundant thyroid disorder worldwide. For decades, levothyroxine was the main effective pharmacological treatment for hypothyroidism. A variety of factors can influence levothyroxine dose, such as genetic variations.
Nada Hamid Rasheed +2 more
doaj +1 more source
Levothyroxine in Pregnancy [PDF]
, 2021 SCOPUS: ch.b ; info:eu-repo/semantics ...
openaire +1 more source
Applied Sciences, 2022 Objective: To compare brain metabolism using [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) in total thyroidectomy patients during hypothyroidism (levothyroxine withdrawal) or under recombinant human thyroid ...
Sílvia D. Almeida +6 more
doaj +1 more source