Results 11 to 20 of about 36,523 (215)

Levothyroxine use and longitudinal changes in thigh muscles in at-risk participants for knee osteoarthritis: preliminary analysis from Osteoarthritis Initiative cohort

open access: yesArthritis Research & Therapy, 2023
Background We examined the association between levothyroxine use and longitudinal MRI biomarkers for thigh muscle mass and composition in at-risk participants for knee osteoarthritis (KOA) and their mediatory role in subsequent KOA incidence.
Bahram Mohajer   +6 more
doaj   +2 more sources

Prevalence and factors associated with chronic use of levothyroxine: A cohort study.

open access: yesPLoS ONE, 2021
ImportanceLevothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use.ObjectiveTo assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with ...
Camilla Janett-Pellegri   +10 more
doaj   +2 more sources

Levothyroxine Therapy in Thyrodectomized Patients

open access: yesFrontiers in Endocrinology, 2021
Administration of the optimal dose of levothyroxine (LT4) is crucial to restore euthyroidism after total thyroidectomy. An insufficient or excessive dosage may result in hypothyroidism or thyrotoxicosis, either one associated with a number of symptoms ...
Paolo Miccoli   +2 more
doaj   +2 more sources

Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population‐based assessment

open access: yesPharmacology Research & Perspectives, 2021
Our study aimed to describe levothyroxine prescription patterns and trends over time among pregnant women with subclinical hypothyroidism (SCH) in the United Kingdom.
Ya‐Hui Yu   +5 more
doaj   +2 more sources

Hyperfiltration and Metabolism Before and After a Low-Calorie, Pre-Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs. [PDF]

open access: yesBasic Clin Pharmacol Toxicol
ABSTRACT Psychotropic drug concentrations increase/decrease with hydrophilicity/lipophilicity after a low‐calorie pre‐bariatric surgery diet. To investigate underlying mechanisms, body weight and serum creatinine/cystatin C changes over the diet period were characterized and suggested to reflect changes in glomerular filtration and metabolic capacity ...
Axelsson MAB, Wallerstedt SM.
europepmc   +2 more sources

Intravenous Levothyroxine for Unstable Brain-Dead Heart Donors.

open access: yesNew England Journal of Medicine, 2023
BACKGROUND Hemodynamic instability and myocardial dysfunction are major factors preventing the transplantation of hearts from organ donors after brain death.
R. Dhar   +8 more
semanticscholar   +1 more source

Medications and Food Interfering with the Bioavailability of Levothyroxine: A Systematic Review

open access: yesTherapeutics and Clinical Risk Management, 2023
Purpose Levothyroxine is a common prescribed drug. Many medications and food, however, can interfere with its bioavailability. The aim of this review was to summarize the medications, food and beverages that interact with levothyroxine and to assess ...
Hanqing Liu   +6 more
semanticscholar   +1 more source

Severity of Fatigue and Its Relationship with TSH before and after Levothyroxine Replacement Therapy in Patients with Primary Hypothyroidism

open access: yesBiomedicines, 2023
Background: Fatigue is a common symptom in hypothyroidism; however, the effect of levothyroxine on fatigue has been little studied. The aim of this study was to evaluate the effect of levothyroxine on fatigue in Latino patients with primary ...
María Guadalupe Ruíz-Pacheco   +11 more
semanticscholar   +1 more source

Effects of levothyroxine replacement therapy on insulin resistance in patients with untreated primary hypothyroidism

open access: yesBMC Research Notes, 2023
Objectives This study investigated the effects of levothyroxine replacement therapy on insulin resistance, lipid profile, and thyroid function in patients with untreated primary hypothyroidism.
Alireza Ostadrahimi   +6 more
semanticscholar   +1 more source

Levothyroxine: Conventional and Novel Drug Delivery Formulations

open access: yesEndocrine reviews, 2022
Although levothyroxine is one of the most prescribed medications in the world, its bioavailability has been reported to be impaired by many factors, including interfering drugs or foods and concomitant diseases, and persistent hypothyroidism with a high ...
Hanqing Liu   +4 more
semanticscholar   +1 more source

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