Results 31 to 40 of about 37,295 (269)

Study protocol: a randomised controlled trial on the clinical effects of levothyroxine treatment for subclinical hypothyroidism in people aged 80 years and over [PDF]

, 2018
Background: Subclinical hypothyroidism is common in older people and its contribution to health and disease needs to be elucidated further. Observational and clinical trial data on the clinical effects of subclinical hypothyroidism in persons aged 80 ...
Blum, M.R., Dekkers, O.M., Den Elzen, W.P.J., Du Puy, R.S., Ford, I., Gussekloo, J., Jukema, J.W., Kean, S., Kearney, P.M., Messow, C.M., Mooijaart, S.P., Peeters, R.P., Poortvliet, R.K.E., Postmus, I., Rodondi, N., Smit, J.W.A., Stott, D.J., van Munster, B.C., Watt, T., Westendorp, R.G.J., Wolffenbuttel, B.H.R.   +20 more
core   +8 more sources

Levothyroxine treatment and cholesterol in hypothyroidism [PDF]

Nature Reviews Endocrinology, 2020
Thyroid status and serum cholesterol levels are intimately linked. Hypothyroidism causes hypercholesterolaemia, which is thought to be resolved after treatment with levothyroxine and normalization of thyroid-stimulating hormone. However, some studies indicate that hypercholesterolaemia persists despite treatment, requiring more frequent use of statins.
Antonio C. Bianco, Peter N. Taylor
openaire   +3 more sources

Levothyroxine Dosage Determination According to Body Mass Index (BMI) After Total Thyroidectomy

Erciyes Medical Journal, 2019
Objective: Currently, postoperative thyroid hormone replacement dosing is weight-based with adjustments and made following Thyroid Stimulating Hormone (TSH) values, which may lead to delayed achievement of euthyroidism and failure in achieving an ...
Hemmat Maghsoudi, Seyed Ehsan Mousavi Toomatari, Naser Agha Mohammadzade, Farzad Najafipour, Sara Akhavan Salamat, Seyed Babak Moosavi Toomatari, Afshin Gharekhani   +6 more
doaj   +1 more source

Study protocol; thyroid hormone replacement for untreated older adults with subclinical hypothyroidism - a randomised placebo controlled trial (TRUST) [PDF]

, 2017
Background: Subclinical hypothyroidism (SCH) is a common condition in elderly people, defined as elevated serum thyroid-stimulating hormone (TSH) with normal circulating free thyroxine (fT4).
Bauer, Douglas, Blum, Manuel, Browne, John, Byrne, Stephen, Collet, Tinh-Hai, Dekkers, Olaf M., Den Elzen, Wendy P.J., Du Puy, Robert, Ford, Ian, Gussekloo, Jacobijn, Hendry, Kirsty, Hurley, Caroline, Jukema, J. Wouter, Kean, Sharon, Kearney, Patricia M., McCarthy, Vera, Mooijaart, Simon, Poortvliet, Rosalinde K.E., Quinn, Terence J., Rodondi, Nicolas, Sattar, Naveed, Smit, Jan W.A., Stott, David J., Watt, Torquil, Westendorp, Rudi G.J.   +24 more
core   +9 more sources

Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis

Case Reports in Endocrinology, 2015
An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor. On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable.
Peter N. Taylor, Arshiya Tabasum, Gina Sanki, David Burberry, Brian P. Tennant, James White, Onyebuchi Okosieme, Andrew Aldridge, Gautam Das   +8 more
doaj   +1 more source

A new mutation in the promoter region of the PAX8 gene causes true congenital hypothyroidism with thyroid hypoplasia in a girl with Down's syndrome [PDF]

, 2014
<b>Background:</b> Thyroid dysfunction is common in newborn infants with Down's syndrome (DS), but defects causing classic thyroid dysgenesis (TD) with permanent congenital hypothyroidism (CH) have not been described.<p></p> ...
Donaldson, Malcolm, Hermanns, Pia, Jones, Jez, Mansor, Mohamed, Pohlenz, Joachim, Schulga, John, Shepherd, Scott   +6 more
core   +1 more source

Levothyroxine use and longitudinal changes in thigh muscles in at-risk participants for knee osteoarthritis: preliminary analysis from Osteoarthritis Initiative cohort

Arthritis Research & Therapy, 2023
Background We examined the association between levothyroxine use and longitudinal MRI biomarkers for thigh muscle mass and composition in at-risk participants for knee osteoarthritis (KOA) and their mediatory role in subsequent KOA incidence.
Bahram Mohajer, Kamyar Moradi, Ali Guermazi, Jennifer S. R. Mammen, David J. Hunter, Frank W. Roemer, Shadpour Demehri   +6 more
doaj   +1 more source

Levothyroxine Absorption Test With the Daily Levothyroxine Dose in Patients With "Refractory Hypothyroidism". [PDF]

J Endocr Soc
Abstract Hypothyroidism is a frequent disease, and oral levothyroxine is the mainstay of its treatment. However, more than 15% of levothyroxine-treated patients fail to achieve the recommended serum TSH level, and “refractory hypothyroidism” is due to either malabsorption, increased metabolism of thyroxine, or nonadherence to treatment ...
Caron P, Tudor C, Grunenwald S.
europepmc   +3 more sources

Changes in Serum TSH and T4 Levels after Switching the Levothyroxine Administration Time from before Breakfast to before Dinner

International Journal of Endocrinology, 2015
Background. Levothyroxine is commonly used in the treatment of patients with hypothyroidism. Levothyroxine is most often administered in the morning, on an empty stomach, in order to increase its oral absorption.
S. Ala, O. Akha, Z. Kashi, A. Bahar, H. Askari Rad, N. Sasanpour, A. Shiva   +6 more
doaj   +1 more source

Use of levothyroxine among pregnant women with subclinical hypothyroidism in the United Kingdom: A population‐based assessment

Pharmacology Research & Perspectives, 2021
Our study aimed to describe levothyroxine prescription patterns and trends over time among pregnant women with subclinical hypothyroidism (SCH) in the United Kingdom.
Ya‐Hui Yu, Kristian B. Filion, Pauline Reynier, Robert W. Platt, Oriana H. Y. Yu, Sonia M. Grandi   +5 more
doaj   +1 more source