Results 41 to 50 of about 51,650 (294)

Design of the Optimal Trial of Combination Therapy

open access: yesFrontiers in Endocrinology, 2020
Patients who take levothyroxine monotherapy to treat hypothyroidism frequently experience residual symptoms despite TSH testing at target levels. Trials have been conducted to evaluate the potential benefit of combination therapy with levothyroxine and ...
Anne R. Cappola
doaj   +1 more source

A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid. Is conservative treatment always advised? [PDF]

open access: yes, 2015
Introduction: Struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common ...
Bianchi, Loredana   +9 more
core   +2 more sources

Levothyroxine Dosage Determination According to Body Mass Index (BMI) After Total Thyroidectomy

open access: yesErciyes Medical Journal, 2019
Objective: Currently, postoperative thyroid hormone replacement dosing is weight-based with adjustments and made following Thyroid Stimulating Hormone (TSH) values, which may lead to delayed achievement of euthyroidism and failure in achieving an ...
Hemmat Maghsoudi   +6 more
doaj   +1 more source

Early detection of biochemically occult autonomous thyroid nodules [PDF]

open access: yes, 2016
Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia   +7 more
core   +1 more source

Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception

open access: yesNew England Journal of Medicine, 2019
Background Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse outcomes.
Rima K. DHILLON-SMITH   +33 more
semanticscholar   +1 more source

Weekly Intramuscular Injection of Levothyroxine following Myxoedema: A Practical Solution to an Old Crisis

open access: yesCase Reports in Endocrinology, 2015
An 82-year-old female with known hypothyroidism was admitted to hospital after being found on the floor. On examination, she was unkempt, confused, bradycardic, hypothermic, and barely arousable.
Peter N. Taylor   +8 more
doaj   +1 more source

Factors influencing the levothyroxine dose in the hormone replacement therapy of primary hypothyroidism in adults

open access: yesReviews in Endocrine & Metabolic Disorders, 2021
Levothyroxine (LT4) is a safe, effective means of hormone replacement therapy for hypothyroidism. Here, we review the pharmaceutical, pathophysiological and behavioural factors influencing the absorption, distribution, metabolism and excretion of LT4 ...
P. Caron   +5 more
semanticscholar   +1 more source

Maternal thyroid function and child educational attainment: prospective cohort study [PDF]

open access: yes, 2018
Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline   +7 more
core   +3 more sources

Changes in Serum TSH and T4 Levels after Switching the Levothyroxine Administration Time from before Breakfast to before Dinner

open access: yesInternational Journal of Endocrinology, 2015
Background. Levothyroxine is commonly used in the treatment of patients with hypothyroidism. Levothyroxine is most often administered in the morning, on an empty stomach, in order to increase its oral absorption.
S. Ala   +6 more
doaj   +1 more source

Ipilimumab, not just another anti-cancer therapy: hypophysitis as side effect illustrated by four case-reports [PDF]

open access: yes, 2014
Ipilimumab is a monoclonal antibody that blocks cytotoxic T-lymphocyte antigen4 (CTLA-4), an inhibitory molecule typically expressed on T cells. Blockade of CTLA-4 induces an overall activation of T cells, including an immune-mediated anti-tumour ...
Brochez, Lieve   +4 more
core   +2 more sources

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