Results 41 to 50 of about 37,295 (269)
The Effects of Simvastatin on the Serum Concentrations of Thyroid Stimulating Hormone and Free Thyroxine in Hypothyroid Patients Treated with Levothyroxine [PDF]
Iranian Journal of Medical Sciences, 2011 Background: Statins, such as simvastatin, are the drugs of choice for the treatment of hypercholesterolemia. On the other hand hypercholesterolmia can occur in hypothyroid patients, who receive levothyroxine.
Mohammad Abbasinazari +2 more
doaj
Levothyroxine monotherapy cannot guarantee euthyroidism in all athyreotic patients. [PDF]
PLoS ONE, 2011 CONTEXT: Levothyroxine monotherapy is the treatment of choice for hypothyroid patients because peripheral T4 to T3 conversion is believed to account for the overall tissue requirement for thyroid hormones.
Damiano Gullo +5 more
doaj +1 more source
Levothyroxine use and the risk of colorectal cancer: a large population-based case–control study
Endocrine Connections, 2022 Objective: Whether an association between oral levothyroxine use, leading to supraphysiological exposure of the colon to thyroid hormones, and risk of colorectal cancer exists in humans is unclear.
Josephina G Kuiper +9 more
doaj +1 more source
Maternal thyroid function and child educational attainment: prospective cohort study [PDF]
, 2018 Objective: To determine if first trimester maternal thyroid dysfunction is a critical determinant of child scholastic performance and overall educational attainment. Design: Prospective cohort study.
Haig, Caroline +7 more
core +3 more sources
Endocrinology, Diabetes & Metabolism Case Reports, 2018 Congenital hypothyroidism requires prompt treatment to prevent adverse health outcomes. Poor intestinal levothyroxine absorption can complicate management. We present a case of a term female newborn with necrotizing enterocolitis (NEC) requiring subtotal
Charlotte S Schömig +2 more
doaj +1 more source
AAPS Open, 2022 Introduction Levothyroxine, the standard-of-care treatment for hypothyroidism, is susceptible to degradation when exposed to light and moisture and is an FDA-designated narrow therapeutic index drug. In this report, we examined how different packaging (e.
Jonathan Chun
doaj +1 more source
Early detection of biochemically occult autonomous thyroid nodules [PDF]
, 2016 Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia +7 more
core +1 more source
Best Practice & Research Clinical Endocrinology & Metabolism, 2015 At present, the drug of choice for the treatment of hypothyroidism is levothyroxine sodium, even though the thyroid gland secretes both thyroxine and 3',3,5-triiodothyronine; the latter is the more active of the two at the cellular level because of its higher affinity for the nuclear thyroid hormone receptors.
Escobar-Morreale, Héctor F. +2 more
openaire +4 more sources
The role of levothyroxine in obstetric practice [PDF]
Annals of Medicine, 2017 Thyroid hormones play a pivotal role in somatic growth, metabolic regulation and neurodevelopment. There is growing evidence regarding adverse obstetric and perinatal consequences of maternal thyroid hypofunction during early stages of pregnancy. These include: early pregnancy loss, preterm delivery and lower intelligence quotient (IQ) in children ...
Inés Velasco, Peter Taylor
openaire +4 more sources
Hypothyroidism and the increased risk of preeclampsia – interpretative factors?
Hypertension in Pregnancy, 2020 Objective To evaluate the causes behind the association between hypothyroidism and the risk of preeclampsia. Methods Checking of individual hospital and birth records from 149 levothyroxine users among 2,508 women in the preeclampsia case–control study ...
Aino Lintula +2 more
doaj +1 more source