Results 181 to 190 of about 18,410 (222)
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HLA Antigens, Lewis Antigens, and Blood Groups in Patients with Testicular Germ-Cell Tumors
Oncology, 2009Clinical observations, epidemiologic data, and results of animal experiments support the theory of genetic anticipation of testicular germ-cell tumors. Attempts to find genetic markers of testicular cancer have yielded conflicting results. We studied blood groups of 577 patients treated for testicular germ-cell tumor (GCT) and controls, Lewis antigens ...
K P, Dieckmann, R, Klän, S, Bünte
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Unravelling the biochemical basis of blood group ABO and Lewis antigenic specificity
Glycoconjugate Journal, 2000The ABO blood-group polymorphism is still the most clinically important system in blood transfusion practice. The groups were discovered in 1900 and the genes at the ABO locus were cloned nearly a century later in 1990. To enable this goal to be reached intensive studies were carried out in the intervening years on the serology, genetics, inheritance ...
W T, Morgan, W M, Watkins
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Evaluation of Lewis blood group antigens and secretor status in pemphigus vulgaris
Clinical and Experimental Dermatology, 2015There has not been publication of any previous study about the role of secretory status or Lewis phenotypes in the mechanisms of pemphigus vulgaris (PV).To evaluate the frequencies of secretory status and Lewis phenotypes in patients with PV compared with healthy controls (HCs) in order determine their roles in this autoimmune disease.In total, 50 ...
M, Shahidi-Dadras, A, Golfeshan
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Lewis blood group antigens defined by monoclonal anti-colon carcinoma antibodies
Archives of Biochemistry and Biophysics, 1984Monoclonal antibodies directed against human cancer cells were prepared by the murine hybridoma technique. These antibodies detect Lewis blood group antigens as determined by indirect solid-phase radioimmunoassay, hapten inhibition studies, and chromatogram binding assay. One monoclonal antibody is specific for the Lea terminal carbohydrate of Gal beta
M, Blaszczyk +8 more
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Neoexpression of ABH and Lewis Blood Group Antigens in Human Hepatocellular Carcinomas2
JNCI: Journal of the National Cancer Institute, 1987Expression of blood group ABH, Lewis, and sialylated-Lea antigens in human hepatocellular carcinomas and the adjacent nontumorous liver tissues was investigated with the use of seven monoclonal antibodies against these carbohydrate determinants.
Yoshio Okada +8 more
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Vox Sanguinis, 1987
Abstract. Monoclonal blood grouping sera provide a means of overcoming difficulties inherent in the use of conventional polyclonal reagents. Two murine monoclonal anti‐Lewis reagents were tested and found to be comparable to conventional reagents for use in red cell phenotyping.
J W, Cowles +3 more
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Abstract. Monoclonal blood grouping sera provide a means of overcoming difficulties inherent in the use of conventional polyclonal reagents. Two murine monoclonal anti‐Lewis reagents were tested and found to be comparable to conventional reagents for use in red cell phenotyping.
J W, Cowles +3 more
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Lewis Blood Group Antigen Expression by Cultured Normal Ureteral Epithelial Cells
Journal of Urology, 1992The importance of Lewis blood group antigens in recurrent urinary tract infections has led to a more detailed study of the expression of these antigens in an in vitro culture system. Expression of A, B, H, and Lewis blood group antigens by primary cultures of ureter epithelial cells was analyzed by flow cytometry.
R A, Gaffney +2 more
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CORRELATION OF HUMORAL IMMUNITY TO LEWIS BLOOD GROUP ANTIGENS WITH RENAL TRANSPLANT REJECTION
Transplantation, 1984Recent studies suggest that the Lewis blood group antigens are important for human renal transplantation. A possible mechanism by which Lewis blood group incompatibility could influence allograft rejection was investigated by measuring Lewis antibodies in sera from renal transplant recipients and appropriate controls using conventional hemagglutination
S, Spitalnik +5 more
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Journal of Leukocyte Biology, 2000
Abstract The expression of the difucosyl-lactosamine type 2 oligosaccharide Lewis Y (LeY) on peripheral blood cells was investigated. As assessed by the reactivity with the mouse anti-LeY monoclonal antibody (mAb) ABL 364 among circulating blood cells, the expression of the LeY oligosaccharide was uniquely restricted to granulocytes ...
M, Dettke, G, Pálfi, H, Loibner
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Abstract The expression of the difucosyl-lactosamine type 2 oligosaccharide Lewis Y (LeY) on peripheral blood cells was investigated. As assessed by the reactivity with the mouse anti-LeY monoclonal antibody (mAb) ABL 364 among circulating blood cells, the expression of the LeY oligosaccharide was uniquely restricted to granulocytes ...
M, Dettke, G, Pálfi, H, Loibner
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Expression of Lewisxand LewisyBlood Group Related Antigens in Fetal Livers
Pediatric Pathology, 1990Aberrant expression of blood group antigens has been observed in human cancers. Lewis(x) (Le(x)) and Lewis(y) (Le(y)) antigens are usually absent from parenchymal cells in the adult human liver, but frequently expressed on cholangiocarcinomas and less frequently on hepatocellular carcinomas.
D S, Heller, S N, Thung
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