Results 31 to 40 of about 4,930,458 (259)
Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
, 2010 Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +1 more source
Stimulation of TM3 Leydig cell proliferation via GABAA receptors: A new role for testicular GABA
Reproductive Biology and Endocrinology, 2004 The neurotransmitter gamma-aminobutyric acid (GABA) and subtypes of GABA receptors were recently identified in adult testes. Since adult Leydig cells possess both the GABA biosynthetic enzyme glutamate decarboxylase (GAD), as well as GABAA and GABAB ...
Krieger Annette +4 more
doaj +1 more source
Ultrasound of a prepubertal Leydig cell tumour of the testis [PDF]
, 2017 Leydig cell tumours of the testis are uncommon. They typically present in a bimodal age distribution between either 5 and 10 years of age, or 20 to 60 years of age.
Long, Gillian +5 more
core +1 more source
Leydig cell aging and hypogonadism [PDF]
Experimental Gerontology, 2015 Leydig cell testosterone (T) production is reduced with age, resulting in reduced serum T levels (hypogonadism). A number of cellular changes have been identified in the steroidogenic pathway of aged Leydig cells that are associated with reduced T formation, including reductions in luteinizing hormone (LH)-stimulated cAMP production, the cholesterol ...
M C, Beattie +4 more
openaire +2 more sources
Radiology Case Reports, 2020 Leydig cell tumors are usually small and resemble normal ovarian stroma, so they are often difficult to localize. Here, we present a rare case in 39-year-old woman which dynamic contrast-enhanced and diffusion-weighted magnetic resonance imaging findings
Kazuya Okamura, MD +5 more
doaj +1 more source
Spermatogenesis and sertoli cell activity in mice lacking Sertoli cell receptors for follicle stimulating hormone and androgen [PDF]
, 2008 Spermatogenesis in the adult male depends on the action of FSH and androgen. Ablation of either hormone has deleterious effects on Sertoli cell function and the progression of germ cells through spermatogenesis.
Baker, P.J. +8 more
core +1 more source
Insulin-like factor 3 (INSL3) and the HPG axis in the male
Frontiers in Endocrinology, 2014 The HPG (hypothalamo-pituitary-gonadal) axis comprises pulsatile GnRH from the hypothalamus impacting on the anterior pituitary to induce expression and release of both LH and FSH into the circulation.
Richard eIvell +3 more
doaj +1 more source
Advanced Science, EarlyView.Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
wiley +1 more source
Effects of FSH on testicular mRNA transcript levels in the hypogonadal mouse [PDF]
, 2009 Follicle stimulating hormone (FSH) acts through the Sertoli cell to ensure normal testicular development and function. To identify transcriptional mechanisms through which FSH acts in the testis we have treated gonadotrophin-deficient hypogonadal (hpg ...
Abel, M.H. +4 more
core +1 more source
Normal testis size, spermatogenesis and Leydig cell development in Leydig cell conditional mutants.
, 2022 (A) Intact testes from one year control and Leydig cell conditional homozygous mutant. (B,C) DAPI fluorescence of epididymis from one year control and Leydig cell conditional mutant.
Vivian J. Bardwell (12119794) +7 more
core +1 more source