Ecotoxicology and Environmental Safety, 2021 Perfluorooctane sulfonate is related to male reproductive dysfunction in rats and humans. However, the underlying mechanism remains unknown. Here, we reported the effects of short-term exposure to perfluorooctane sulfonate on the regeneration of Leydig ...
Baiping Mao +7 more
doaj +1 more source
Leydig cells express neural cell adhesion molecules in vivo and in vitro [PDF]
, 1992 The neural cell adhesion molecule (NCAM) polypeptides are expressed by numerous tissues during embryonic development, where they are involved in cell-cell interactions.
Lahr, G. +7 more
core +1 more source
, 2022 Glucocorticoids are steroids involved in key physiological processes such as development, metabolism, inflammatory and stress responses and are mostly used exogenously as medications to treat various inflammation-based conditions.
Darbey, Annalucia LL +25 more
core +1 more source
Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours [PDF]
, 2007 Background: Sertoli-Leyclig cell tumours of the ovary account for only 0.2% of malignant ovarian tumours. Two-thirds of all patients become apparent due to the tumour's hormone production. Methods: A 41-year-old patient (gravida 4, para 4) presented with
Kuemper, Caroline +6 more
core +1 more source
Aldosterone Blocks Rat Stem Leydig Cell Development In Vitro
Frontiers in Endocrinology, 2018 Aldosterone (ALDO) is a primary endogenous mineralocorticoid, appearing as the main hormone controlling sodium and water homeostasis. Its emerging role in the development of many organs has gained interest over the past few years.
Jingwei Zhang +9 more
doaj +1 more source
Transcriptional Profiling of Luteinizing Hormone Receptor-Deficient Mice Before and after Testosterone Treatment Provides Insight into the Hormonal Control of Postnatal Testicular Development and Leydig Cell Differentiation [PDF]
, 2010 Luteinizing hormone (LH) is a key regulator of male fertility through its effects on testosterone secretion by Leydig cells. Transcriptional control of this is, however, currently poorly understood.
Affara, Nabeel +5 more
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Dibutyltin Dichloride Retards Leydig Cell Developmental Regeneration in Adult Rat Testis
Frontiers in Pharmacology, 2018 Dibutyltin dichloride (DBTCl), widely used as plastic stabilizer, can cause comprehensive toxicity. The present study aims to investigate the effects of DBTCl on rat Leydig cell developmental regeneration and characterize the related mechanism.
Xiande Huang, Taoye Ma, Yongsheng Yin
doaj +1 more source
Bilateral Leydig Cell Tumor in a Capuchin Monkey (Sapajus apella): Case Report. [PDF]
J Med PrimatolABSTRACT Leydig cell tumors (LCTs) are uncommon in nonhuman primates (NHPs). A bilateral LCT was identified in a 20‐year‐old male capuchin monkey (Sapajus apella) maintained under human care. Ultrasonography revealed a right testicular nodule, while necropsy identified bilateral testicular masses. Histopathology confirmed bilateral LCT.
Favacho ELB +6 more
europepmc +2 more sources
Testicular development in mice lacking receptors for follicle stimulating hormone and androgen [PDF]
, 2012 Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through ...
Abel, M. +11 more
core +2 more sources
Leydig cell tumor and hyperplasia : a review
Analytical and quantitative cytology and histology, 2007 We describe the role of Leydig cells in normal, hyperplastic and neoplastic testis. Recent acquisitions on etiology and pathobiology of Leydig cell proliferations, unusual microscopic presentations and clinical and morphologic features predictive of ...
M. Colecchia +6 more
core +4 more sources