Results 71 to 80 of about 11,952,476 (292)

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

PATHOMORPHOLOGICAL FEATURES OF TESTICULAR TUMORS IN DOGS

Ukrainian Journal of Veterinary Sciences, 2020
The research was conducted to study the morphological, clinical, and macroscopic characteristics of the different histological types of canine testicular tumors.
N. B. KOLYCH
doaj   +1 more source

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]

, 2019
LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito, Fattorini, Giorgio, Franco, Giorgio, Gianfrilli, Daniele, Isidori, Andrea M, Lenzi, Andrea, Leonardo, Costantino, Pofi, Riccardo, Pozza, Carlotta, Sbardella, Emilia, Tarsitano, Maria Grazia, Tenuta, Marta, Testis, Unit   +12 more
core   +1 more source

Sertoli Cells Maintain Leydig Cell Number and Peritubular Myoid Cell Activity in the Adult Mouse Testis

PLoS ONE, 2014
The Sertoli cells are critical regulators of testis differentiation and development. In the adult, however, their known function is restricted largely to maintenance of spermatogenesis.
D. Rebourcet, P. O’Shaughnessy, Ana Monteiro, Laura Milne, Lyndsey Cruickshanks, N. Jeffrey, F. Guillou, T. Freeman, R. Mitchell, Lee B. Smith   +9 more
semanticscholar   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Numeric and volumetric changes in Leydig cells during aging of rats [PDF]

Acta Cirúrgica Brasileira, 2017
Purpose: To analyze the effects of aging in rats on the nuclear volume, cytoplasmic volume, and total volume of Leydig cells, as well as their number.
Bruno Vinicius Duarte Neves, Fernando Lorenzini, Djanira Veronez, Eduardo Pereira de Miranda, Gabriela Duarte Neves, Rogério de Fraga   +5 more
doaj   +1 more source

Autocrine androgen action is essential for Leydig cell maturation and function, and protects against late-onset Leydig cell apoptosis in both mice and men

The FASEB Journal, 2014
Leydig cell number and function decline as men age, and low testosterone is associated with all “Western” cardio‐metabolic disorders. However, whether perturbed androgen action within the adult Leydig cell lineage predisposes individuals to this late ...
L. O’Hara, K. McInnes, Ioannis Simitsidellis, Stephanie Morgan, N. Atanassova, J. Słowikowska-Hilczer, K. Kula, M. Szarras-Czapnik, Laura Milne, R. Mitchell, Lee B. Smith   +10 more
semanticscholar   +1 more source

Protective Effects of Fenugreek and Stevia Extracts on Dexamethasone‐Induced Testicular Damage in a Rat Model

Food Safety and Health, EarlyView.
Fenugreek and stevia extracts protect against dexamethasone‐induced testicular damage in male rats by enhancing antioxidant defenses, improving sperm quality, and restoring hormonal balance, highlighting their potential as natural therapeutics for preventing corticosteroid‐induced reproductive toxicity.
Mosab Gad, Medhat Ibrahim A. Omar, Mohammed I. Elkhateeb, Ahmed A. Zaky   +3 more
wiley   +1 more source

NR2F2 regulation of interstitial cell fate in the embryonic mouse testis and its impact on differences of sex development

Nature Communications
Testicular fetal Leydig cells produce androgens essential for male reproductive development. Impaired fetal Leydig cell differentiation leads to differences of sex development including hypospadias, cryptorchidism, and infertility.
Martín Andrés Estermann, Sara A. Grimm, Abigail S. Kitakule, Karina F. Rodriguez, Paula R. Brown, Kathryn McClelland, Ciro M. Amato, Humphrey Hung-Chang Yao   +7 more
doaj   +1 more source

Immunolocalization of steroidogenic enzymes in the vaginal mucous of Galea spixii during the estrous cycle. [PDF]

, 2017
BackgroundThe synthesis of sex steroids is controlled by several enzymes such as17α-hydroxylase cytochrome P450 (P450c17) catalyzing androgen synthesis and aromatase cytochrome P450 (P450arom) catalyzing estrogen synthesis, both of which must complex ...
Assis Neto, Antônio Chaves de, Conley, Alan James, de Oliveira, Moacir Franco, Dos Santos, Amilton Cesar, Oliveira, Gleidson Benevides, Viana, Diego Carvalho   +5 more
core   +1 more source