Results 51 to 60 of about 21,083 (177)

A Sertoli-Leydig ovarian tumor presenting as ovarian torsion: A case report

open access: yesCase Reports in Women's Health
Torsion occurs as a complication in 10% of cases of ovarian tumors. It predominantly occurs in benign ones, while malignant tumors are less prone to torsion.
Samia Tligui   +6 more
doaj   +1 more source

Effects of hypocholesterolemia and chronic hormonal stimulation on sterol and steroid metabolism in a Leydig cell tumor.

open access: yesJournal of Lipid Research, 1981
The studies presented herein were done to investigate the effects of drug-induced hypocholesterolemia and chronic hormonal stimulation on cholesterol metabolism and steroid biosynthesis in a functional Leydig cell tumor. It was found that 4-aminopyrazolo(
M Ascoli
doaj   +1 more source

Nuclear localization of β-catenin in Sertoli cell tumors and other sex cord–stromal tumors of the testis: an immunohistochemical study of 87 cases [PDF]

open access: yes, 2015
The diagnosis and subclassification of Sertoli cell tumors (SCT) of the testis are often challenging to general surgical pathologists because of the rarity of the tumors. Immunohistochemical study to date has limited diagnostic value.
Ulbright, Thomas M., Zhang, Chen
core   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Cryptorchidism: Novel genetic insights into CCDC149 mutations

open access: yesAndrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du   +8 more
wiley   +1 more source

Adipocyte-Like Differentiation in a Posttreatment Embryonal Rhabdomyosarcoma. [PDF]

open access: yes, 2015
We describe a 16-year-old boy with rhabdomyosarcoma, consistent with embryonal subtype, of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision.
Balitzer, Dana   +2 more
core   +4 more sources

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

open access: yesAndrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby   +10 more
wiley   +1 more source

The Effect of Aqueous Lessertia frutescens Extract on TM3 Leydig Cells Exposed to TNF-α in vitro

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: Extractions of Lessertia frutescens (Lf) are shown to have immune modulation, anti-inflammatory and antioxidant properties. However, Lf is also cytotoxic, antiproliferative, and pro-apoptotic in vitro.
Kristian Leisegang   +3 more
doaj   +1 more source

Spinal cord compression by a solitary metastasis from a low grade leydig cell tumour: a case report and review of the literature [PDF]

open access: yes, 2008
Background Leydig tumour is rare and there are only three cases with metastatic disease reported. Case presentation A 52 year-old Caucasian male was admitted, on emergency basis to the Orthopaedic Department with six weeks history of increasing ...
Lucas Jonathan D   +4 more
core   +1 more source

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

open access: yesAndrology, EarlyView.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto   +12 more
wiley   +1 more source

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