Results 101 to 110 of about 16,604,758 (298)

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Cellular and hormonal disruption of fetal testis development in sheep reared on pasture treated with sewage sludge [PDF]

, 2005
The purpose of this study was to evaluate whether experimental exposure of pregnant sheep to a mixture of environmental chemicals added to pasture as sewage sludge (n = 9 treated animals) exerted effects on fetal testis development or function ...
Paul, Catriona, Kyle, Carol E, McKinnell, Chris, Sharpe, Richard M, Catriona Paul, Richard M. Sharpe, Hayley Scott, Chris McKinnell, Scott, Hayley, Rhind, Stewart M, Carol E. Kyle, Stewart M. Rhind   +11 more
core   +1 more source

Effects of Osteocalcin on Synthesis of Testosterone and INSL3 during Adult Leydig Cell Differentiation

International Journal of Endocrinology, 2019
Proliferation and differentiation of adult Leydig cells are mainly completed in puberty. In many studies, apart from normal postnatal development process, it is widely indicated that, through administrating EDS, Leydig cell population is eliminated and ...
Gulfidan Coskun, Leman Sencar, Abdullah Tuli, Dilek Saker, Mustafa Muhlis Alparslan, Sait Polat   +5 more
doaj   +1 more source

Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development

Frontiers in Endocrinology, 2019
Fibroblast growth factor 1 (FGF1) is reported to be expressed in the testis. How FGF1 affects stem Leydig cell development remains unclear. Here, we report the effects of FGF1 on rat stem Leydig cell development in an ethane dimethane sulfonate (EDS ...
Lanlan Chen, Lanlan Chen, Xiaoheng Li, Yiyan Wang, Tiantian Song, Huitao Li, Lubin Xie, Linchao Li, Xianwu Chen, Leikai Ma, Yong Chen, Yao Lv, Xingwang Li, Ren-Shan Ge, Ren-Shan Ge   +14 more
doaj   +1 more source

The Role of Foxo3 in Leydig Cells

Yonsei Medical Journal, 2015
Foxo3 in female reproduction has been reported to regulate proliferation of granulose cells that form follicles. There are no reports so far that discuss on the role of Foxo3 in males. This study was designed to outline the role of Foxo3 in the testes.Testes from mice at birth to postpartum week (PPW) 5 were isolated and examined for the expression of ...
Choi, Young Suk, Song, Joo Eun, Kong, Byung Soo, Hong, Jae Won, Novelli, Silvia, Lee, Eun Jig   +5 more
openaire   +3 more sources

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Steroidogenic effects of Taraxacum officinale extract on the levels of steroidogenic enzymes in mouse Leydig cells

Animal Cells and Systems, 2018
In this study, we investigated the steroidogenic effect of Taraxacum officinale extract on mouse TM3 Leydig cells, which produce male hormones by increasing the levels of steroidogenic enzymes.
H. Chung, Y. Noh, Min Su Kim, Ara Jang, C. Lee, S. Myung   +5 more
semanticscholar   +1 more source

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Propofol Inhibits Androgen Production in Rat Immature Leydig Cells

Frontiers in Pharmacology, 2019
Background: Propofol is a widely used anesthetic. Whether propofol inhibits androgen production by rat Leydig cells and the underlying mechanism remains unclear.
Yiyan Wang, Fei Ge, Xiaoheng Li, Chaobo Ni, Keyang Wu, Wenwen Zheng, Yong Chen, Qingquan Lian, Ren-Shan Ge   +8 more
doaj   +1 more source

Semen quality in patients with testicular cancer is associated with age and with greatly elevated levels of beta human chorionic gonadotropin

Andrology, EarlyView.
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann, Johanna Hochmuth‐Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Marta Godlewska, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf   +9 more
wiley   +1 more source