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Biology of Reproduction, 2021
Leydig cells play a critical role in male reproductive physiology, and their dysfunction is usually associated with male infertility. Melatonin has an important protective and regulatory role in these cells.
Minghui Yang +15 more
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Leydig cells play a critical role in male reproductive physiology, and their dysfunction is usually associated with male infertility. Melatonin has an important protective and regulatory role in these cells.
Minghui Yang +15 more
semanticscholar +1 more source
Seminars in Cell and Developmental Biology, 2021
Stem cells are specialized cells that can renew themselves through cell division and can differentiate into multi-lineage cells. Mesenchymal stem cells are adult stem cells that exist in animal and human tissues.
Xiaoheng Li +6 more
semanticscholar +1 more source
Stem cells are specialized cells that can renew themselves through cell division and can differentiate into multi-lineage cells. Mesenchymal stem cells are adult stem cells that exist in animal and human tissues.
Xiaoheng Li +6 more
semanticscholar +1 more source
Molecular regulation of steroidogenesis in endocrine Leydig cells
Steroids, 2015Jacques J. Tremblay
exaly +2 more sources
Leydig Cell and Spermatogenesis
2021Leydig cells of the testis have the capacity to synthesize androgen (mainly testosterone) from cholesterol. Adult Leydig cells are the cell type for the synthesis of testosterone, which is critical for spermatogenesis. At least four steroidogenic enzymes take part in testosterone synthesis: cytochrome P450 cholesterol side chain cleavage enzyme, 3β ...
Ren-Shan, Ge, Xiaoheng, Li, Yiyan, Wang
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Free Radical Biology & Medicine, 2020
Oxidative stress has been described as a key driver of Leydig cell apoptosis. Melatonin has antioxidative and antiapoptotic effects, but the potential effects and mechanism of melatonin on oxidative stress and apoptosis in rooster Leydig cells remain ...
Yangyunyi Dong +5 more
semanticscholar +1 more source
Oxidative stress has been described as a key driver of Leydig cell apoptosis. Melatonin has antioxidative and antiapoptotic effects, but the potential effects and mechanism of melatonin on oxidative stress and apoptosis in rooster Leydig cells remain ...
Yangyunyi Dong +5 more
semanticscholar +1 more source
Physiologic Interactions Between Macrophages and Leydig Cells
Experimental Biology and Medicine, 2006 The purpose of this minireview is to present information concerning the morphologic and functional relationship between testicular macrophages and Leydig cells. Although data concerning the negative influence of macrophage-derived products on testicular
James C Hutson
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The cross talk of adrenal and Leydig cell steroids in Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 2019Glucocorticoid is secreted by adrenal cortex, which binds to intracellular glucocorticoid and mineralocorticoid receptors to regulate steroidogenesis-related gene expression and testosterone production in Leydig cells. Glucocorticoid receptor activity shows inhibitory action on Leydig cell steroidogenesis, while mineralocorticoid receptor activity ...
Yiyan, Wang +5 more
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INSL3 Expression in Leydig Cell Hyperplasia and Leydig Cell Tumors
Applied Immunohistochemistry & Molecular Morphology, 2019Insulin-like 3 (INSL3) is a hormone produced by Leydig cells (LCs) and leads to physiological testicular descent during embryonic development. We investigated the expression of INSL3 by immunohistochemistry in normal LCs, in Leydig cell tumor (LCT) (n=17 including 15 testes and 2 ovaries) and in Leydig cell hyperplasia (LCH) (n=10).
Nelli S, Lakis +5 more
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2018
Leydig cells (LC) are found in the testicular interstitial tissue surrounding the seminiferous tubules. Their primary function is to produce testosterone (T), which is crucial for maintaining spermatogenesis and supporting extra-testicular androgenic, psychological, and anabolic functions.
Huhtaniemi, I., Teerds, K.J.
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Leydig cells (LC) are found in the testicular interstitial tissue surrounding the seminiferous tubules. Their primary function is to produce testosterone (T), which is crucial for maintaining spermatogenesis and supporting extra-testicular androgenic, psychological, and anabolic functions.
Huhtaniemi, I., Teerds, K.J.
openaire +2 more sources