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Leydig-cell tumour of the testis
International Urology and Nephrology, 1980Leydig cell tumor of the testis is an uncommon occurrence. A case is reported here which had two interesting features. One was extensive calcification and the other an abundant lipid deposition within the tumour cells. The pathogenesis of calcification is discussed.
R, Malik +4 more
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Urology, 1979
In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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In adult patients with Leydig cell tumor of the testis, endocrinologic signs occur in 30 per cent of the cases and often precede the onset of a palpable testicular mass. Gynecomastia is the most common endocrinologic manifestation and probably is due to increased estrogen secretion by the Leydig cells.
A A, Caldamone +3 more
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Differentiation of adult Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 1995Adult Leydig cells originate within the testis postnatally. Their formation is a continuous process involving gradual transformation of progenitors into the mature cell type. Despite the gradual nature of these changes, studies of proliferation, differentiation and steroidogenic function in the rat Leydig cell led to the recognition of three distinct ...
L, Benton, L X, Shan, M P, Hardy
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Archives of Gynecology and Obstetrics, 2001
Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
T, Lantzsch +5 more
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Interleukin 6 inhibits the differentiation of rat stem Leydig cells.
Molecular and Cellular Endocrinology, 2017Inflammation causes male hypogonadism. Several inflammatory cytokines, including interleukin 6 (IL-6), are released into the blood and may suppress Leydig cell development.
Yiyan Wang +11 more
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The ultrastructure of testicular tumours in the dog: II. Leydig cells and Leydig cell tumours
Journal of Comparative Pathology, 1978Abstract The ultrastructural appearance of testicular Leydig cells in healthy dogs as well as canine Leydig cell tumours is described. The cells of most Leydig cell tumours (10 out of 13) showed the typical characteristics of normal Leydig cells: abundant smooth endoplasmic reticulum, mitochondria with tubular inner structures and numerous small and ...
D, von Bomhard +2 more
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Malignant Feminizing Leydig Cell Tumor
Journal of Urology, 1984AbstractA patient with a feminizing malignant Leydig cell tumor is presented. Hormonal assays revealed increased production of prolactin, estradial, and total estrogens. Eleven years after the onset of his disease he remains clinically well.
C M, Shapiro, A, Sankovitch, W J, Yoon
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Cell Biology of Leydig Cells in the Testis
2004This article reviews results on differentiation, structure, and regulation of Leydig cells in the testes of rodents and men. Two different populations-fetal and adult Leydig cells-can be recognized in rodents. The cells in these two populations are different in ultrastructure, life span, capacity for androgen synthesis, and mechanisms of regulation.
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Assessing Autophagy in the Leydig Cells
2018Autophagy is an important intracellular degradation system which is implicated in many physiological and pathological processes. During autophagy, cytosolic constituents such as organelles and macromolecules are engulfed by autophagosome, and then they fuse with lysosomes for degradation and recycle of the engulfed components within the autolysosome to
Hui, Gao, Chao, Liu, Wei, Li
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[Leydig-cell tumors of the testicle].
Annali italiani di chirurgia, 1990Leydig's cells tumor account for 1-2% of all testicular tumors. The authors report a rare case of benign Leydig's cells tumor in a young man with gynecomastia. They examine the embryogenesis, the hormonal modifications, the criteria of malignancy, the treatment and results. They present a review of the literature pertaining to this rare tumors.
GUERRIERO O +5 more
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