Results 241 to 250 of about 16,604,758 (298)
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1983
The role of the testis in the development of masculine features has been known for literally thousands of years. It is, however, only within the past 150 years that we have begun to understand how the testes have these effects. The location and appearances of the cells that now bear his name were first described by Von Leydig in 1857.
Y, Hodgson, B, Hudson
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The role of the testis in the development of masculine features has been known for literally thousands of years. It is, however, only within the past 150 years that we have begun to understand how the testes have these effects. The location and appearances of the cells that now bear his name were first described by Von Leydig in 1857.
Y, Hodgson, B, Hudson
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Aflatoxin B1 impairs leydig cells through inhibiting AMPK/mTOR-mediated autophagy flux pathway.
Chemosphere, 2019Aflatoxin B1 (AFB1), a potential endocrine disrupter, has been shown to induce hepatotoxicity in animal models, but the effects of AFB1 on Leydig cell function are unclear.
Xian-Wu Chen +12 more
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Environmental Pollution, 2019
It is very important to explore the potential harm and underlying mechanism of fluoride due to the extensive distribution and the significant health risks of fluoride in environment.
Chen Liang +8 more
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It is very important to explore the potential harm and underlying mechanism of fluoride due to the extensive distribution and the significant health risks of fluoride in environment.
Chen Liang +8 more
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Archives of Andrology, 1986
The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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The ultrastructure of Leydig cell hyperplasia is described. The hyperplastic Leydig cells differ morphologically from normal Leydig cells as well as from Leydig tumor cells. They have less smooth endoplasmic reticulum and less lipofuscin pigment in their cytoplasm, and the nuclear membrane shows more irregular indentations than normal Leydig cells.
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Physiology and Pathology of the Leydig Cell
New England Journal of Medicine, 1980LEYDIG cells, the interstitial cells of the testes, lie between the seminiferous tubules and produce androgenic steroids. The secretion of testosterone in men has been thought to be regulated by a feedback system in which luteinizing hormone from the anterior pituitary stimulates the conversion of cholesterol to testosterone.
Howard L. Bleich +2 more
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Role of autophagy in di-2-ethylhexyl phthalate (DEHP)-induced apoptosis in mouse Leydig cells.
Environmental Pollution, 2018Di-2-ethylhexyl phthalate (DEHP) has been widely used as a plasticizer in industry. DEHP can cause testicular atrophy, yet the exact mechanism remains unclear.
Yin-Jin Sun +8 more
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Control of steroidogenesis in Leydig cells
The Journal of Steroid Biochemistry and Molecular Biology, 1992Luteinizing hormone (LH) interacts with its plasma membrane receptor to stimulate steroidogenesis not only via cyclic AMP but also other pathways which include arachidonic acid and leukotrienes and regulation of chloride and calcium channels. The same stimulatory pathways may lead to desensitization and down-regulation of the LH receptor and ...
B A, Cooke +4 more
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Leydig Cell in Idiopathic Varicocele
European Urology, 1990In a group of 31 patients with idiopathic varicocele (IV), testicular biopsy showed a decreased tubular diameter, hyperplasia in the number of Leydig's cells (LC; many with cytoplasmic vacuolization and atrophy) and a decrease in the number of positive LC in testicular tissue sections stained with the testosterone peroxidase-antiperoxidase method ...
J J, Sirvent +5 more
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Toxicology Letters, 2018
Nickel (Ni) can disorder testosterone synthesis in rat Leydig cells, whereas the mechanisms remain unclear. The aim of this study was to investigate the role of reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPKs) in Ni-induced ...
Aijie Han +10 more
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Nickel (Ni) can disorder testosterone synthesis in rat Leydig cells, whereas the mechanisms remain unclear. The aim of this study was to investigate the role of reactive oxygen species (ROS) and mitogen-activated protein kinases (MAPKs) in Ni-induced ...
Aijie Han +10 more
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Congenital Leydig cell hyperplasia
Histopathology, 1988The testes and epididymes collected at autopsy from 21 newborns showed apparent Leydig cell hyperplasia which was studied by light and electron microscopy. Twelve newborns were the sons of diabetic mothers, two had undergone rhesus isoimmunization, two were twins of a non‐diabetic mother, three had Beckwitz‐Widemann's syndrome, and two had ...
M, Nistal +2 more
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