Results 31 to 40 of about 1,193,334 (327)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Evaluation of gonadotropin responses and response times according to two different cut-off values in luteinizing hormone releasing hormone stimulation test in girls

Indian Journal of Endocrinology and Metabolism, 2020
Background: In this study, we aimed to evaluate FSH, LH responses obtained during LHRH-ST according to two different cut-off values, to determine the diagnostic response times, and to find the optimal blood collection times that could reduce the economic
Servan Ozalkak, Semra Çetinkaya, Fatma Can Budak, Şenay Savaş Erdeve, Zehra Aycan   +4 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

LHFTL: A novel SSD performance optimisation approach using the LH index [PDF]

Journal of Electrical and Electronics Engineering, 2021
Flash Translation Layer (FTL) based Solid State Drives SSDs have a crucial role for flash storage devices for many reasons (i.e., lower energy consumption, better performance and less heating).
MOHAMMED Boucetta, L'HADI Boughani, MOHAMMED MAHMOUD Abu Shquier, MOURAD Amad, WALID KHALED Hidouci   +4 more
doaj  

Static polarizability of two-dimensional hole gases

, 2010
We have calculated the density-density (Lindhard) response function of a homogeneous two-dimensional (2D) hole gas in the static (omega=0) limit. The bulk valence-band structure comprising heavy-hole (HH) and light-hole (LH) states is modeled using ...
Bastard G, Michele Governale, Schliemann J, Thomas Kernreiter, Ulrich Zülicke, Winkler R, Yu P Y, Ziman J M   +7 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

IL-1 Receptor Antagonist Anakinra Inhibits the Effect of IL-1β- Mediated Osteoclast Formation by Periodontal Ligament Fibroblasts

Biology
Rheumatoid arthritis and periodontitis are comorbidities that share mutual pathways. IL-1β is a pro-inflammatory cytokine that plays a crucial role in both diseases.
Elizabeth Steemers, Wael M. I. Talbi, Jolanda M. A. Hogervorst, Ton Schoenmaker, Teun J. de Vries   +4 more
doaj   +1 more source

Pituitary and ovarian hormones: is their plasma concentration affected by litter size in primiparous lactating rabbit does?

World Rabbit Science, 2021
Genetic selection in commercial rabbit lines based on litter size has positively improved the number of kits suckling, presumably to weaning. Although it has been proven that the energetic balance of primiparous does is due to the need to satisfy ...
Carlota Fernández-Pacheco, Pilar Millán, María Rodríguez, Nora Formoso-Rafferty, Beatriz Velasco, Pilar G. Rebollar   +5 more
doaj   +1 more source

Accuracy of the Ovulon Fertility Monitor to Predict and Detect Ovulation [PDF]

, 1998
The purpose of this pilot study was to correlate the three biologic markers of the Ovulon fertility monitor (a long-term predictive peak about 6 days before ovulation, a short-term predictive peak about 1 day before ovulation, and a nadir at the time of ...
Fehring, Richard, Schlaff, William D
core   +1 more source

Large Quark Rotations, Neutrino mixing and Proton Decay [PDF]

, 2000
Right-handed (RH) rotations do not play a role in the Standard Model, and only the differences of the LH mixing angles are involved in ${\bf V}_{\scr \textrm{CKM}}$. This leads to the huge freedom in the fermionic mass matrices.
Abdurashitov, Acampora, Achiman, Achiman, Achiman, Achiman, Achiman, Achiman, Achiman, Albright, Albright, Altarelli, Ambrosio, Antoniadis, Arneodo, Athanassopoulos, Babu, Bando, Bemporad, Berezhiani, Bilenky, Bolz, Branco, Buchmüller, Buras, Carsten Merten, Chaichian, Chang, Chang, Chanowitz, Chanowitz, Checko, Cleveland, Davidson, del Aguila, Deshpande, Dine, Eitel, Flanz, Fritzsch, Fritzsch, Froggatt, Fukuda, Fukuda, Fukugita, Gavela, Gell-Mann, Georgi, Georgi, Gipson, Giudice, Giusti, Hampel, Harvey, Hayato, Hirata, Ibañez, Kane, Keymer, Kim, Kuzmin, Langacker, Langacker, Langacker, Lee, Lola, Lucas, Masiero, Merten, Mikheyev, Mohapatra, Mohapatra, Nath, Nomura, Pati, Pati, Peccei, Pilaftsis, Rajpoot, Ramond, Robinett, Romanino, Ross, Shifman, Shiozawa, Smy, Spurio, Tosa, Wolfenstein, Yanagida, Yoav Achiman   +90 more
core   +4 more sources