Results 61 to 70 of about 11,867 (232)

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis [PDF]

open access: yes, 2016
Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage.
Bartholin, Laurent   +5 more
core   +1 more source

Effect of LHCGR Gene Polymorphism (rs2293275) on LH Supplementation Protocol Outcomes in Second IVF Cycles: A Retrospective Study

open access: yesFrontiers in Endocrinology, 2021
Infertility is a major concern for couples wanting to have progeny. Despite recent advances in the field of IVF, success rates still need improvement. Understanding the patient’s variability and addressing it with personalized interventions may improve ...
Ramaraju GA   +9 more
doaj   +1 more source

Determination of biological activity of gonadotropins hCG and FSH by Forster resonance energy transfer based biosensors [PDF]

open access: yes, 2017
Determination of biological activity of gonadotropin hormones is essential in reproductive medicine and pharmaceutical manufacturing of the hormonal preparations.
Allikalt, Anni   +4 more
core   +1 more source

Role of Single Nucleotide Variants in FSHR, GNRHR, ESR2 and LHCGR Genes in Adolescents with Polycystic Ovary Syndrome

open access: yesDiagnostics, 2021
Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women, affecting up to 16.6% of reproductive-age women. PCOS symptoms in adolescents comprise oligomenorrhoea/amenorrhoea and biochemical and/or clinical hyperandrogenism ...
Lasma Lidaka   +9 more
doaj   +1 more source

Expanded carrier screening: A current perspective [PDF]

open access: yes, 2018
Prenatal carrier screening has expanded to include a large number of genes offered to all couples considering pregnancy or with an ongoing pregnancy.
Al-Kouatly, Hb   +12 more
core   +1 more source

Association of a missense mutation in the luteinizing hormone/choriogonadotropin receptor gene (LHCGR) with superovulation traits in Chinese Holstein heifers

open access: yesJournal of Animal Science and Biotechnology, 2012
Background Upon binding luteinizing hormone in the ovary, the luteinizing hormone/choriogonadotropin receptor (LHCGR) is necessary for follicular maturation and ovulation, as well as luteal function.
Yu Yong   +6 more
doaj   +1 more source

Molecular determinants of a competent bovine corpus luteum: first vs final wave dominant follicles [PDF]

open access: yes, 2016
Reproductive management in cattle requires the synchrony of follicle development and oestrus before insemination. However, ovulation of follicles that have not undergone normal physiological maturation can lead to suboptimal luteal function.
B K Campbell   +11 more
core   +1 more source

Association analysis of LHCGR variants and polycystic ovary syndrome in Punjab: a case–control approach

open access: yesBMC Endocrine Disorders, 2022
Abstract Background Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that affects women at their child bearing age. The exact etiology is uncertain, however the involvement of multiple genes and environmental interactions has been proposed for the advancement of PCOS.
Sukhjashanpreet Singh   +4 more
openaire   +3 more sources

The spectrum of phenotypes associated with mutations in steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) includes severe penoscrotal hypospadias in 46,XY males without adrenal insufficiency [PDF]

open access: yes, 2009
OBJECTIVE. Hypospadias is a frequent congenital anomaly but in most cases an underlying cause is not found. Steroidogenic factor 1 (SF-1, NR5A1, Ad4BP) is a key regulator of human sex development and an increasing number of SF-1 (NR5A1) mutations are ...
Achermann, J.C.   +9 more
core   +2 more sources

Long-Term Treatment With Letrozole in a Boy With Familial Male-Limited Precocious Puberty

open access: yesFrontiers in Endocrinology, 2022
BackgroundThe long-term follow-up in children with familial male-limited precocious puberty (FMPP) who were treated with letrozole, triptorelin, and spironolactone is limited, especially considering the efficiency and safety.ObjectiveWe describe the ...
Xin Yuan   +4 more
doaj   +1 more source

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