Results 31 to 40 of about 327 (244)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang   +8 more
wiley   +1 more source

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

open access: yesAdvanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale   +4 more
wiley   +1 more source

The Liar Paradox from the Wittgensteinian Perspective

open access: yesStudia Semiotyczne, 2019
DOI: http://doi.org/10.26333/sts.xxxi2.09 Our approach to the liar paradox is based on the Wittgensteinian approach to semantic and logical paradoxes.
Jakub Gomułka, Jan Wawrzyniak
doaj  

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Was man Sprach- und Kommunikationswissenschaftler über die „Lüge“ fragen darf – und was nicht

open access: yesCahiers d’Études Germaniques, 2014
This contribution presents various theoretical approaches taken by linguists, philosophers and communication experts when dealing with “lies”. While structural linguists lack professional access to lies altogether because of their exclusive focus on ...
Clemens Knobloch
doaj   +1 more source

Fluorinated Deep Eutectic Gel Electrolytes with Simultaneously Enhanced Mechanical Strength and Ionic Conductivity for Solid‐State Lithium Metal Batteries

open access: yesAdvanced Materials, EarlyView.
The synergistic integration of rigid polyacrylamide (PAM) and flexible poly(N,N‐dimethylacrylamide) (PDMA) phases offers exceptional toughness to suppress lithium dendrites, simultaneously enhancing mechanical strength and ionic conductivity. ABSTRACT Gel polymer electrolytes for lithium‐metal batteries face an inherent trade‐off between mechanical ...
Hao Long   +6 more
wiley   +1 more source

Il paradosso di Epimenide: come una citazione può creare un falso originale [PDF]

open access: yesParole Rubate, 2014
The origins of the famous and much-discussed ‘paradox of the liar’ – that is to say, someone claiming to be saying the truth and at the same time declaring to be lying – have been dated back to a polemical passage allegedly composed by the ancient Cretan
Nicola Reggiani
doaj  

The Liar-paradox in a Quantum Mechanical Perspective

open access: yesFoundations of Science, 1999
16 pages, 1 ...
Aerts, Diederik   +2 more
openaire   +4 more sources

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