Results 161 to 170 of about 4,474,959 (386)

Special Libraries, March 1915 [PDF]

open access: yes, 1915
Volume 6, Issue 3https://scholarworks.sjsu.edu/sla_sl_1915/1002/thumbnail ...
Special Libraries Association
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Design and synthesis of screening libraries based on the muurolane natural product scaffold

open access: hybrid, 2012
Emma C. Barnes   +4 more
openalex   +2 more sources

Special Libraries, May 1919 [PDF]

open access: yes, 1919
Volume 10, Issue 4https://scholarworks.sjsu.edu/sla_sl_1919/1003/thumbnail ...
Special Libraries Association
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Information Outlook, May 2006 [PDF]

open access: yes, 2005
Volume 10, Issue 5https://scholarworks.sjsu.edu/sla_io_2006/1004/thumbnail ...
Special Libraries Association
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Information Outlook, March 2007 [PDF]

open access: yes, 2006
Volume 11, Issue 3https://scholarworks.sjsu.edu/sla_io_2007/1002/thumbnail ...
Special Libraries Association
core   +2 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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