Results 21 to 30 of about 2,190,696 (310)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Evaluating the Effectiveness of Tools for Online Database Instruction

open access: yesCommunications in Information Literacy, 2014
The intent of this study was to evaluate the Guide on the Side (Gots), an online learning tool developed by the University of Arizona Libraries, and a screencast tutorial for teaching information literacy and database searching skills.
Yvonne Mery   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

VLA Paraprofessional Forum 2011 Conference Report: Libraries: Paving the Way for Success

open access: yesVirginia Libraries, 2011
The nineteenth annual Virginia Library Association Paraprofessional Forum Conference was held May 22–24, 2011, at the Holiday Inn Select/Koger South Conference Center in Chesterfield County.
Virginia Libraries
doaj  

Designing the Cyberinfrastructure for Spatial Data Curation, Visualization, and Sharing

open access: yesIASSIST Quarterly, 2017
Widely used across disciplines such as natural resources, social sciences, public health, humanities, and economics, spatial data is an important component in many studies and has promoted interdisciplinary research development.
Yue Li, Nicole Kong, Stanislav Pejša
doaj   +1 more source

Rethink, Reuse, Recycle: Turning an Existing Workshop into a Virtual Opportunity for Outreach and Engagement [PDF]

open access: yesMarketing Libraries Journal, 2021
This case study of using a webinar series as a library marketing technique shares the process, communications, and assessment results from a well-attended online event, “Summer of Citations.” An in-person citation management software workshop for ...
Wardell, Jason   +2 more
doaj  

Special Libraries, Winter 1986 [PDF]

open access: yes, 1986
Volume 77, Issue 1https://scholarworks.sjsu.edu/sla_sl_1986/1000/thumbnail ...
Special Libraries Association
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy