Results 71 to 80 of about 599,649 (257)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Faiss Library

open access: yesIEEE Transactions on Big Data
Vector databases typically manage large collections of embedding vectors. Currently, AI applications are growing rapidly, and so is the number of embeddings that need to be stored and indexed. The Faiss library is dedicated to vector similarity search, a core functionality of vector databases.
Matthijs Douze   +8 more
openaire   +4 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

E-Journal Metrics for Collection Management: Exploring Disciplinary Usage Differences in Scopus and Web of Science

open access: yesEvidence Based Library and Information Practice, 2016
Objective – The purpose was to determine whether a relationship exists between journal downloads and either faculty authoring venue or citations to these faculty, or whether a relationship exists between journal rankings and local authoring venues or ...
Katherine Chew   +3 more
doaj   +1 more source

The Effectiveness of Library Instruction for Graduate/Professional Students: A Systematic Review and Meta-Analysis

open access: yesEvidence Based Library and Information Practice, 2020
Objective - This study sought to assess the effectiveness of library instruction for increasing information literacy skills and/or knowledge among graduate and professional students.
Adelia Grabowsky, Liza Weisbrod
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

The Implementation of Keenious at Carnegie Mellon University

open access: yesJournal of eScience Librarianship
In the fall of 2022, the Carnegie Mellon University (CMU) Libraries began investigating Keenious—an artificial intelligence (AI)-based article recommender tool—for a possible trial implementation to improve pathways to resource discovery and assist ...
Ashley Werlinich   +3 more
doaj   +2 more sources

The Quality Study of Provincial Websites of Iranian Public Libraries Foundation with WQET and Suggestions to Improve [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2015
Purpose: The aim of this study is to evaluate the quality of provincial websites of Iran Public Libraries Foundation (IPLF) by WQET evaluation tool. Methodology: Survey method was used for implementation of this research.
Mahtab Teimouri   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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