Results 71 to 80 of about 7,839,381 (313)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The death of the library? The place of the book and the reader at the time of dispersion

Visualidades, 2015
With the immateriality of the book, which is its place in contemporary society? Does the library, as a repository of books make sense when the word became ubiquitous and virtually capable of being read at any point on earth?
Joaci Pereira Furtado
doaj   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Impact of constituent development fund allocations on the performance of South Sulawesi provincial library and archives office

Otoritas: Jurnal Ilmu Pemerintahan
The decision of the South Sulawesi Provincial Government to suspend the Regional House of Representatives grant, known as the Constituent Development Fund, adversely affected the programs and activities of the South Sulawesi Provincial Library and ...
Moh Ilham A Hamudy, Mutiara Lulu Annisa, M S Rifki   +2 more
doaj   +1 more source

You\u27ve Gotta Read This: Summer Reading at Musselman Library (2006)

, 2006
Each year Musselman Library asks Gettysburg College faculty, staff, and administrators to help create a suggested summer reading list to inspire students and the rest of our campus community to take time in the summer to sit back, relax, and read.
Musselman Library,
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Guidelines for library service for young adults

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
Directrius per a la planificació i avaluació de serveis adreçats a adolescents en biblioteques ...
IFLA. Section of Library for Children and Young Adults
doaj  

Friends of Musselman Library Newsletter Fall 2014

, 2014
Table of Contents: From the Director: Gettysburgreat: The Campaign for Our College (Robin Wagner); Popular Middle East Series Continues; Letter from Edgar Rice Burroughs Explains Origin of Tarzan\u27s Name; Library Celebration Owl & Nightingale\u27s ...
Musselman Library,
core   +1 more source