Results 51 to 60 of about 25,503,651 (307)

The Library [PDF]

The Library, 1889
n ...
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Activity of Institute of Book Chamber and its Value in Preservation of Cultural Heritage in XX - the beginning of the XXI century

Управленческое консультирование, 2018
This article is devoted to the analysis and characterization of the structure and activities of the Institute book chamber in the field of cultural heritage preservation of the former Soviet Union and contemporary Russian Federation in the period of XX -
Gennadii Nikolaevich Khrapkov
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

An efficient and information-rich biochemical method design for fragment library screening on ion channels

BioTechniques, 2010
Drug discovery requires a simple, rapid, and cost-effective method for the early identification of novel leads and elimination of poor candidates.
Andrew J. Thompson, Mark H.P. Verheij, Rob Leurs, Iwan J.P. De Esch, Sarah C.R. Lummis   +4 more
doaj   +1 more source

Kaufman Library Faculty/Staff Newsletter, Spring 2017

, 2017
Spring 2017 issue of the Georgia Gwinnett College Daniel J. Kaufman Library & Learning Center newsletter for faculty and staff. 6 pages. Contents: "Farewell Gene Ruffin", "Introducing Primo", "Featuring!
Kaufman Library, GGC Library
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

For the Library [PDF]

Science, 1977
  +8 more sources

Penerapan Sistem Sirkulasi Perpustakaan Berbasis Slims Pada SMA IT Al Fityah Pekanbaru

Dinamisia, 2020
In the world of education there is now an electronic-based learning system that can be used for distance learning. The change in learning from the manual base to electronic precisely the internet indicates a global change to make it easier for humans to ...
Loneli Costaner, Guntoro, Yuhelmi
doaj   +1 more source

Kaufman Library Faculty/Staff Newsletter, Fall 2016

, 2016
Fall 2016 issue of the Georgia Gwinnett College Daniel J. Kaufman Library & Learning Center newsletter for faculty and staff. 7 pages. Contents: "Library Dedication", "Quiet Reading Room Exhibit", "Research Services and the Information Literacy Omnibus",
Kaufman Library, GGC Library
core