Results 51 to 60 of about 27,040,215 (308)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Penerapan Sistem Sirkulasi Perpustakaan Berbasis Slims Pada SMA IT Al Fityah Pekanbaru
In the world of education there is now an electronic-based learning system that can be used for distance learning. The change in learning from the manual base to electronic precisely the internet indicates a global change to make it easier for humans to ...
Loneli Costaner, Guntoro, Yuhelmi
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
СТАНОВЛЕНИЕ ОБРАЗОВАНИЯ В ТОМСКОЙ ГУБЕРНИИ: ИЗ АРХИВНЫХ ФОНДОВ ШКОЛЬНОГО МУЗЕЯ
Основная цель статьи – показать историю становления и развития начальных училищ и гимназий (мужских и женских) в сибирских территориях периода ХVII – начала ХХ в.
Ревякина Валентина Ивановна +1 more
doaj +1 more source
Libraries and the REF: how do librarians contribute to research excellence?
Librarians support research in a wide variety of ways. However, librarians may not always receive recognition for the valuable contributions they make to the research life cycle or research environments.
Dominic Walker
doaj +1 more source
Kaufman Library Faculty/Staff Newsletter, Spring 2017
Spring 2017 issue of the Georgia Gwinnett College Daniel J. Kaufman Library & Learning Center newsletter for faculty and staff. 6 pages. Contents: "Farewell Gene Ruffin", "Introducing Primo", "Featuring!
Kaufman Library, GGC Library
core
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Knjižnična građa tiskana u tiskari Franjevačkog samostana u Osijeku – začetak tiskarstva u Slavoniji
Printing in Osijek began with the arrival of the Franciscans and the establishment of the first printing house in the area in 1735. The Franciscans were allowed to open a small printing house in the monastery for the needs of the province.
Marina Vinaj, Ivana Knežević Križić
doaj +1 more source

