Results 71 to 80 of about 1,914,269 (259)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Henryk Sienkiewicz’s Works as a Factor in the Struggle for the Revival of the Polish State: According to the materials of the Department of Library Collections and Historical Collections of V. I. Vernadskyi National Library of Ukraine

Київські історичні студії
Having lost statehood at the end of the 18th century, the people of the Polish-Lithuanian Commonwealth desperately tried to regain it, organizing the November Uprising in 1830, and later the January Uprising in 1863–1864.
Ivanna Gurzhiy
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Competències professionals per als bibliotecaris dels serveis de referència i atenció a l'usuari

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2003
Directriu elaborada la RUSA Task Force on Professional Competencies per proveïr a bibliotecaris, biblioteques i centres d’informació d’una pauta modèlica sobre les competències essencials per reeixir en els serveis de referència i atenció a l’usuari.
American Library Association. Reference and User Services Association
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Directrius per a la preparació d'una bibliografia

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2002
Traducció al català de les Guidelines for the preparation of a bibliography de la RUSA’s Standards and Guidelines Committee. Aquestes directrius reflecteixen els desenvolupaments tecnològics des de l’àmplia difusió de les bibliografies a internet i fan ...
American Library Association. Reference and User Services Association
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Quereinsteigende qualifizieren, motivieren, inspirieren

GMS Medizin – Bibliothek – Information
At the end of March 2024, the first certificate course for career changers in the library profession was successfully completed by the Weiterbildunszentrum (Continuing Education Centre) of the FU Berlin in cooperation with the Association of Information ...
Engelkenmeier, Ute
doaj   +1 more source

The Role of the Libraries in the Norwegianization Policy 1880-1905

Proceedings from the Document Academy, 2015
This paper discusses the role of libraries in the implementation of the Norwegianization policy towards the Sámi and Kven minorities in Norway. This question has not been written about or debated in the library history of Norway.
Geir Grenersen
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source