Results 41 to 50 of about 21,503,426 (309)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Libraries and Founders of Libraries [PDF]

open access: yesNotes and Queries, 2010
This comprehensive volume, first published in 1864, covers the history of libraries from classical times to the nineteenth century, principally in England but also further afield. The author was an influential figure in the founding of municipal libraries in nineteenth-century Britain and regarded access to good libraries as crucial to education and ...
  +4 more sources

Analyzing Information about a Hajj Pilgrimage in Indonesia in the Rare Newspaper Collection of The National Library of Indonesia

open access: yesRecord and Library Journal, 2020
Background of the study: Indonesia is a country whose the largest number of Muslims in the world.  Every year, many Indonesian Muslims come to Mecca to perform hajj pilgrimage.
Frial Ramadhan Supratman
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

A Library is Not a Library is Not a Library

open access: yes, 2016
A library is not a library is not a library because not all ‘libraries’ face the same challenges and not all librarians do the same jobs. The narrative we need to see more of is that Library and Information Science skills are today more needed than ever before.
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Spotlight on Special Libraries: The National Sporting Library and Museum

open access: yesVirginia Libraries, 2012

National Sporting Library and Museum Staff
doaj  

The newspaper Slovenec in Slovenian libraries:possibilities of conservation-restoration treatment and reproduction

open access: yesKnjižnica, 2010
The purpose of the research was to gain an overview of the holdings of Slovenec in Slovenian libraries and to state the uniqueness of its original binding kept by the libraryof the Institute of Contemporary History in Ljubljana (hereafter referred to ...
Jedert Vodopivec, Anja Devetak
doaj   +1 more source

The Library [PDF]

open access: yesThe Library, 1889
n ...
openaire   +1 more source

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