Results 31 to 40 of about 7,881,105 (312)

“What Library?”

open access: yesSchool Libraries Worldwide, 2023
Although charter schools are a growing segment of the US education market, they are less likely than traditional public or private schools to have dedicated library facilities, staffing, or services. Currently there is little data about what services charter schools provide to support literacy, research, or technology skill building - services commonly
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spotlight on Special Libraries: The National Sporting Library and Museum

open access: yesVirginia Libraries, 2012

National Sporting Library and Museum Staff
doaj  

The newspaper Slovenec in Slovenian libraries:possibilities of conservation-restoration treatment and reproduction

open access: yesKnjižnica, 2010
The purpose of the research was to gain an overview of the holdings of Slovenec in Slovenian libraries and to state the uniqueness of its original binding kept by the libraryof the Institute of Contemporary History in Ljubljana (hereafter referred to ...
Jedert Vodopivec, Anja Devetak
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Activity of Institute of Book Chamber and its Value in Preservation of Cultural Heritage in XX - the beginning of the XXI century

open access: yesУправленческое консультирование, 2018
This article is devoted to the analysis and characterization of the structure and activities of the Institute book chamber in the field of cultural heritage preservation of the former Soviet Union and contemporary Russian Federation in the period of XX -
Gennadii Nikolaevich Khrapkov
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

An efficient and information-rich biochemical method design for fragment library screening on ion channels

open access: yesBioTechniques, 2010
Drug discovery requires a simple, rapid, and cost-effective method for the early identification of novel leads and elimination of poor candidates.
Andrew J. Thompson   +4 more
doaj   +1 more source

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