Results 31 to 40 of about 7,881,105 (312)
Although charter schools are a growing segment of the US education market, they are less likely than traditional public or private schools to have dedicated library facilities, staffing, or services. Currently there is little data about what services charter schools provide to support literacy, research, or technology skill building - services commonly
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Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Spotlight on Special Libraries: The National Sporting Library and Museum
National Sporting Library and Museum Staff
doaj
The purpose of the research was to gain an overview of the holdings of Slovenec in Slovenian libraries and to state the uniqueness of its original binding kept by the libraryof the Institute of Contemporary History in Ljubljana (hereafter referred to ...
Jedert Vodopivec, Anja Devetak
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RIPK4 function interferes with melanoma cell adhesion and metastasis
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
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This article is devoted to the analysis and characterization of the structure and activities of the Institute book chamber in the field of cultural heritage preservation of the former Soviet Union and contemporary Russian Federation in the period of XX -
Gennadii Nikolaevich Khrapkov
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Drug discovery requires a simple, rapid, and cost-effective method for the early identification of novel leads and elimination of poor candidates.
Andrew J. Thompson +4 more
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