Results 51 to 60 of about 713,296 (247)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Assessment of corporate social responsibility practices in selected public libraries in South-West and North-Central, Nigeria

International Journal of Corporate Social Responsibility
This study explored corporate social responsibility practices in selected public libraries in south-west and north-central Nigeria. The study adopts multiple case-study design, and qualitative research approach.
Ismail Olatunji Adeyemi, Boluke Favour Abiona, Adetunji Idris Adebisi, Khudro Iyabo Ishola, Halleluyah David Ogunlowo   +4 more
doaj   +1 more source

Relation extraction for biological pathway construction using node2vec

BMC Bioinformatics, 2018
Background Systems biology is an important field for understanding whole biological mechanisms composed of interactions between biological components.
Munui Kim, Seung Han Baek, Min Song
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Library and Information Science Internship

Pakistan Journal of Information Management & Libraries
This study explores whether Library and Information Science students from three universities who participated in experiential learning through internship programs have identical or different experiences during their internships under selected internship
Noel W. Cabfilan, Nick W. Sibaen, Duong Thi Phuong Chi, Leilani A. Basa   +3 more
doaj  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Visibility of Library and Information Science and Science Communication in Iran [PDF]

International Journal of Information Science and Management
This study examines how newspapers in Iran have presented library and information science (LIS) to society; how the media understand library and information science as a discipline; and how authors of articles in LIS journals collaborate with members of ...
Zahra Ojagh, Golnessa Galyani Moghaddam
doaj   +1 more source

Retracted: Hotspot Mining in the Field of Library and Information Science under the Environment of Big Data. [PDF]

J Environ Public Health, 2023
Environmental And Public Health JO.
europepmc   +1 more source