Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A Survey Study of Librarians' Knowledge and Skills in the Application of Reference Services based views' Kovacks (Case study: Mazandaran Public University Libraries) [PDF]
Objective: The aim of the study was to assess the status of knowledge and skills in the use of references services based on the views' Kovacks (critical thinking, analysis questions, interviewing, organizing information, Find reference resources, and ...
Ahmad Shabani +2 more
doaj +1 more source
Understanding EBLIP at an organizational level: an initial maturity model [PDF]
Objective - Existing research around evidence based practice in the LIS (library and information science) professional context over the past two decades has captured the experience of individual practitioners, rather than the organization as a whole ...
Howlett, Alisa, Thorpe, Clare
core +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Slovene specialized text corpus of Library and Information Science – An advanced lexicographic tool for library terminology research [PDF]
To support the research in the field of library and information science terminology and dictionary construction in Slovene language a specialized text corpus has been designed and constructed.
Kanič, Ivan
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ukrainian studio specialties: 061 'Journalism (Publishing and Editing) " 029 "Information, Library and Information Science (Library Science, Bibliography and information )" [PDF]
Робоча програма Українські студії для студентів спеціальності 061 "Журналістика (Видавнича справа та редагування)", 029 "Інформаційна, бібліотечна та архівна справа (Бібліотекознавство, бібліографознавство та інформаційна)" Розробники: Іванюк Олег ...
Іванюк, Олег Леонідович
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Health Information Needs of Breast Cancer Survivors: An Umbrella Review
Purpose. The aim of this umbrella review was to identify the main information needs of breast cancer survivors. Since several reviews have already been done on this topic, conducting an umbrella review not only combines their results but also gives a ...
Nahid Gavili +3 more
doaj +1 more source
Is the World After All Just a Dream? [PDF]
DocPerform is a multi and interdisciplinary research project based at City, University of London. Led by members of the Department of Library & Information Science, it comprises scholars and practitioners from the fields of performing arts and library ...
Dunne, J., Robinson, L.
core +1 more source

