Results 31 to 40 of about 887,740 (305)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Memaksimalkan peran perpustakaan sebagai sumber belajar di Sekolah Menengah Atas Muhammadiyah 1 Ponorogo

Berkala Ilmu Perpustakaan dan Informasi, 2022
Introduction. This research analyses efforts made by the library of Muhammadiyah Senior High School 1 Ponorogo in maximising the role of library as a source of learning as issued by the International Federation of Library Associations and Institution.
Anna Nurhayati, Riyanto Riyanto, Moh. Rif’an   +2 more
doaj   +1 more source

IFLA Congress in Italy for the fourth time , Libraries create futures: building on cultural heritage : final programme, Milan, Italy, 23-27 August 2009 [PDF]

, 2009
Welcome of the Chair of the Italian National Committee. IFLA Congress comes back to Italy for the fourth time: 1929, 1951, 1964, and now 2009. In June 1929, in the Marciana Library (Venice), Mr.
Guerrini, Mauro
core  

CANDELS/GOODS-S, CDFS, ECDFS: Photometric Redshifts For Normal and for X-Ray-Detected Galaxies [PDF]

, 2014
We present photometric redshifts and associated probability distributions for all detected sources in the Extended Chandra Deep Field South (ECDFS).
Ashby, Matthew L. N., Barro, Guillermo, Bender, Ralf, Brightman, Murray, Brusa, Marcella, Buchner, Johannes, Budavári, Tamás, Dahlen, Tomas, Donley, Jennifer L., Faber, Sandra M., Ferguson, Henry C., Galametz, Audrey, Georgakakis, Antonis, Grazian, Andrea, Grogin, Norman A., Guo, Yicheng, Hathi, Nimish P., Hsu, Li-Ting, Huang, Kuang-Han, Kocevski, Dale D., Koekemoer, Anton M., Lucas, Ray A., McGrath, Elizabeth, Mobasher, Bahram, Nandra, Kirpal, Peth, Michael, Rangel, Cyprian, Rosario, David J., Salvato, Mara, Szalay, Alexander S., Trump, Jonathan R., Willner, S. P.   +31 more
core   +5 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Myanmar Libraries after the 'Opening Up'

Journal of Information Science Theory and Practice, 2017
This article assesses the recent development of libraries in Myanmar and efforts to build the sector's capacity leading up to and after the first democratic elections held in the country in nearly 50 years, at the end of 2015.
Bradley, Fiona
doaj   +1 more source

Connecting British Columbia (Canada) school libraries and student achievement: A comparison of higher and lower performing schools with similar overall funding [PDF]

, 2011
Research over time has established associations between components of the school library and student achievement. This study was designed to investigate these associations in schools in British Columbia (Canada) where the government provides equitable ...
Haycock, Ken
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Changing with the Times? Library Associations and New Librarians. [PDF]

, 2007
To determine what services and programs of national library associations are most valuable to newer librarians. As young librarians enter the workforce, many are deciding whether or not to join and become involved with library associations such as SLA ...
Isenburg, Megan V, Kipnis, Daniel G, Pernell, Rebecca   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source