Results 51 to 60 of about 189,887 (259)

EBLIDA's action in Europe

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2004
EBLIDA is the European Bureau of Library, Information and Documentation Associations. EBLIDA is an independent umbrella association of national library, information, documentation and archive associations and institutions in Europe. EBLIDA was founded in
Britt Marie Häggström
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Che cos’è una biblioteca ‘normale’?

open access: yesAIB Studi, 2022
Giuseppe Vitiello
doaj   +1 more source

Bibliothekspolitik im föderalen Staat. Der lange Abschied vom nationalen ‚Planungs- und Einheitlichkeitsparadigma‘.

open access: yeso-bib. Das offene Bibliotheksjournal, 2015
Für die häufig diagnostizierte Durchsetzungsschwäche der deutschen Bibliothekspolitik respektive ihrer Institutionenverbände und berufsständischen Organisationen von ihrer Neu- oder Wiederbegründung in der entstehenden Bundesrepublik an bis heute wird ...
Harald Herbert Pilzer
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Activity of the Odessa library association in the 1920's.

open access: yesVìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Bìblìotekoznavstvo, Bìblìografoznavstvo, Knigoznavstvo, 2018
Article Viktor Sokolov «Activities Odessa library association in the 1920-s» explores the features of the formation, structure, basic forms and methods of work of the Odessa library association against the background of major trends of library ...
В. Ю. Соколов
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

World Library and Information Congress: 69th IFLA Conference: August 1-9, 2003

open access: yesIssues in Science and Technology Librarianship, 2004
Summary of events at the The World Library and Information Congress: 69th International Federation of Library Associations General Conference and Council in Berlin, Germany in August of 2003. 
Ray Schwartz
doaj   +1 more source

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