Results 71 to 80 of about 24,850,540 (303)

Improving Z39.50 Interoperability: Z39.50 Profiles and Testbeds for Library Applications [PDF]

open access: yes, 2001
An operating assumption for the networked environment is that many different information systems need to interoperate for users to successfully discover and retrieve distributed resources. Meaningful interoperability is often elusive.
Moen, William E.
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Membership of the Library and Information Association of South Africa (LIASA) among library and information science workers in KwaZulu-Natal

open access: yesSouth African Journal of Libraries and Information Science, 2009
A study was undertaken in 2007 among library and information service (LIS) workers in KwaZulu-Natal (KZN) to investigate LIASA membership trends. The objectives of the study were to investigate: 1) the extent to which workers in library and information ...
Musa Khomo, Jaya Raju
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Libraries On the Hill:

open access: yesPartnership: The Canadian Journal of Library and Information Practice and Research
This exploratory study analyzes the advocacy practices and outputs of three national associations representing libraries and organizations of various types: the Canadian Association of Research Libraries (CARL), the Canadian Urban Libraries Council ...
Merran Carr-Wiggin   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Help a library association [1988]

open access: yes, 1988
Brochure outlining the work of the IFLA Round Table for the Management of Library Associations, later the IFLA Management of Library Associations ...
IFLA Round Table for the Management of Library Associations
core  

Library Politics: a missing link in Library and Information Science. Some considerations about the recent Lectio magistralis by Claudia Lux

open access: yesJLIS.it, 2021
The text refers to the lecture recently held at the University of Florence by Claudia Lux, former president of IFLA, in order to clarify the relationship between public and academic libraries and Library politics, an emerging issue for  researchers in ...
Maria Enrica Vadalà
doaj   +2 more sources

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