Results 61 to 70 of about 24,850,540 (303)
Activity of the Odessa library association in the 1920's.
Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Bìblìotekoznavstvo, Bìblìografoznavstvo, Knigoznavstvo, 2018 Article Viktor Sokolov «Activities Odessa library association in the 1920-s» explores the features of the formation, structure, basic forms and methods of work of the Odessa library association against the background of major trends of library ...
В. Ю. Соколов
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
World Library and Information Congress: 69th IFLA Conference: August 1-9, 2003
Issues in Science and Technology Librarianship, 2004 Summary of events at the The World Library and Information Congress: 69th International Federation of Library Associations General Conference and Council in Berlin, Germany in August of 2003.
Ray Schwartz
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Tıp ve Sağlık Bilimleri Kütüphaneciliğinde Ulusal ve Uluslararası Dernek Oluşumları / Formation of National and International Associations of Medical and Health Sciences Libraries [PDF]
Bilgi Dünyası, 2007 Medical libraries play important roles in classifying, storing andproviding access to medical information. Medical libraries are in steady development ever since 1850’s. This study reviews the formation of associations among modern medical libraries, and
Güssün Güneş
doaj
International health library associations urge the ICMJE to seek information specialists as peer reviewers for knowledge synthesis publications. [PDF]
J Med Libr Assoc, 2021 Iverson S +5 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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The article is about Library Associations Contributions to the United Nations Sustainable Development Goals.
IFLA Management of Library Associations Section Standing Committee
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source