Results 31 to 40 of about 368,010 (306)

Records, Responsibility, and Power: An Overview of Cataloging Ethics

, 2021
Ethics are principles which provide a framework for making decisions that best reflect a set of values. Cataloging carries power, so ethical decision-making is crucial.
Martin, Jennifer M.
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Compliance with Organizational Professioanal Codes of Ethics by the Iran Public Libraries Foundation Staff in Yazd Province [PDF]

تحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2013
Purpose: This research examined the  compliance with of professional codes of ethics public library staff  in the province of Yazd in years 2010-2011. Methodology: The research method is descriptive.
Mosayeb Rezaei, Ahmad Shabani, Seyed Ali Siadat, Fatemeh Naderi Kharaji   +3 more
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Influence of Professional Library Privacy Ethics on the Management of Digitally Transformed Public Library Patron Data: An Exploratory Study Among Australian Public Library Staff

, 2023
Public libraries in Australia are free and open to the whole community, including vulnerable and marginalised groups, and hold positions as trusted institutions.
Caroline Beatty (18046933)
core   +1 more source

The ethical dimension of personal health monitoring in the armed forces: a scoping review

BMC Medical Ethics
Background Personal Health Monitoring (PHM) has the potential to enhance soldier health outcomes. To promote morally responsible development, implementation, and use of PHM in the armed forces, it is important to be aware of the inherent ethical ...
Dave Bovens, Eva van Baarle, Kirsten Ziesemer, Bert Molewijk   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Covert censorship in libraries : a discussion paper [PDF]

, 2005
Librarians, through their professional associations, have long been committed to the social justice principle of free access to information. External censorship challenges to library collections threaten this principle overtly.
Moody, Kim, Kim Moody
core  

An Act of Balance

Nordisk Kulturpolitisk Tidsskrift
This paper presents an analysis of how library professionals in Sweden and Denmark perceive the democratic role of the library profession in the polarised political landscape of today.
Lisa Engström, Bo Skøtt, Hanna Carlsson, Fredrik Hanell, Joacim Hansson   +4 more
doaj   +1 more source