Results 51 to 60 of about 353,857 (262)

Bringing Order to Chaos Ethically: “Cataloging Code of Ethics” and critical cataloging

open access: yesBosniaca
Goal: The goal of this paper is to address the ethics in cataloging and the concept of critical cataloging, as a sub-movement of critical librarianship, as well as to highlight the intersection of ethics with critical in cataloging.
Dalila Mirović
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Enabling ethics mechanisms in the governance of algorithmic artificial persons (ALAP)

open access: yesJournal of Responsible Technology
In the global context of a ‘new social contract’ and a ‘flourishing world’, ethics mechanisms such as principles, guidelines, recommendations, standards, frameworks and checklists, are being established by public and private organisations and governments
Siri Padmanabhan Poti   +2 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Effectiveness and cost-effectiveness of a home-based functional exercise programme for community-dwelling frail older adults, ACTIVE-AGE@home, provided by professionals and volunteers: protocol of a pragmatic randomised controlled trial

open access: yesBMJ Open
Ethics and dissemination Ethics approval has been obtained from the Medical Ethics Committee of UZ Brussel (O.G. 016), Peer reflection group Biomedical Ethics, Laarbeeklaan 101, 1090 Brussels.
Wim Peersman   +10 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Ethics and Cyber Libraries: Challenges Facing the Values and Ethics in LIS

open access: yesSLIS Connecting, 2021
Cyber libraries face many challenges when it comes to access. These challenges can lead to cyber libraries failing in following the guidelines for the values and ethics of the LIS professional. Some authors have argued that cyber libraries are the future of libraries. They argue that patrons want information immediately at their fingertips.
openaire   +3 more sources

URGENSI MATERI PEMBELAJARAN AKHLAK K.H. HASYIM ASY’ARI DALAM MENGHADAPI TANTANGAN PEMBELAJARAN ABAD 21

open access: yesScaffolding: Jurnal Pendidikan Islam dan Multikulturalisme, 2020
21st century learning discourse is getting bigger in the current global world. All countries are competing to prepare the best possible human resources. It's just that if not accompanied by morals will backfire for the country.
Ahmad Dwi Nur Khalim
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Digital assistive technologies to support community-dwelling older adults: an interpretative synthesis of experienced benefits and harms

open access: yesSSM: Qualitative Research in Health
Background: Digital assistive technology (DigAT) holds promise for reducing healthcare costs, improving access to care, and supporting independent living for older adults.
Kasper Kruithof   +4 more
doaj   +1 more source

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