Results 31 to 40 of about 2,418,346 (237)

Rare books as historical objects: a case study of the Elmer E. Rasmuson Library rare books collection [PDF]

open access: yes, 2016
Thesis (M.S.) University of Alaska Fairbanks, 2015Once upon a time all the books in the Arctic were rare books, incomparable treasures to the men and women who carried them around the world.
Korotkova, Ulyana Aleksandrovna   +1 more
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

University Scholar Series: Mary Pickering [PDF]

open access: yes, 2010
Auguste Comte: An Intellectual Biography On November 17, 2010 Mary Pickering spoke in the University Scholar Series hosted by Provost Gerry Selter at the Dr. Martin Luther King, Jr. Library.
Pickering, Mary
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Final Performance Report [PDF]

open access: yes
ArkansasThe goal of the project is to get a basic understanding of the condition of physical collections throughout the state while providing free basic preservation training for those responsible for collections.Institute of Museum and Library ...
Arkansas State Parks, the Arkansas History Commission, the Arkansas State Library, and Amigos Library Services
core  

The Twelve Years Truce (1609). Peace, Truce, War, and Law in the Low Countries at the Turn of the 17th Century [PDF]

open access: yes, 2015
Book review of LESAFFER (Randall), ed., The Twelve Years Truce (1609) : peace, truce, war, and law in the Low Countries at the turn of the 17th century, Leiden/Boston, Martinus Nijhoff/Brill, 2014, IX + 297 p.
Dhondt, Frederik
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

State promotion of local public goods: The case of public libraries, 1880-1929 [PDF]

open access: yes, 2016
The public library movement of the late nineteenth and early twentieth centuries led to a significant expansion of library services across the United States.
Kevane, Michael J, Sundstrom, William A.
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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