Results 251 to 260 of about 3,217,388 (336)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

A framework for reconfigurable production line changeover task planning based on large language model. [PDF]

Sci Rep
Hou J, Yan L, Qiang H.
europepmc   +1 more source

DCAF13 Safeguards Hematopoietic Stem Cells via RRS1‐Regulated Ribosome Biogenesis

Advanced Science, EarlyView.
This study establishes DCAF13 as an essential regulator for hematopoietic stem cell (HSC) function. Its deletion in mice causes lethal pancytopenia and HSC depletion. Mechanistically, DCAF13 interacts with RRS1 and mediates its non‐degradative K27‐linked ubiquitination, thereby stabilizing RRS1 to maintain ribosome biogenesis and protein translation ...
Mengke Li, Yuxin Wu, Shuai Zhou, Peipei Tang, Jiaming Wei, Ling Liu, Zhenyi Wang, Deyang Shi, Shengnan Yuan, Qingyu Zhang, Shihui Wang, Qing Zhang, Huan Zhao, Rui Zhang, Yingying Wang, Shiwei Yang, Xiangli Chen, Xiaojing Shi, Guangzhi Liu, Yuwei Zhang, Jinming Li, Xu Dong Zhang, Rick F Thorne, Dongping Wei, Zumin Zhu, Song Chen   +25 more
wiley   +1 more source

Chinese Graduate Health Science Students' Perceptions of Teaching Pedagogies on Their Educational Experience. [PDF]

Occup Ther Int
Benson JD, Simpson RC.
europepmc   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Introducing professional drug information resources to non-healthcare undergraduates: a case report on promoting drug information literacy. [PDF]

J Med Libr Assoc
Rhee HY, Rhew K.
europepmc   +1 more source

Slide-tape library instruction.

Bulletin of the Medical Library Association, 2010
V B, Hall, D, Krautheim, B S, Hansra
openaire   +1 more source

"Is this professionally correct?": understanding the criteria nurses use to evaluate information. [PDF]

J Med Libr Assoc
Patterson B, Diekema AR, Hopkins EBS, Wilson D, Schvaneveldt N.   +4 more
europepmc   +1 more source

Assessment of two designs for an Oral surgery Postoperative Leaflet. [PDF]

Acta Odontol Latinoam
Gagliardi-Lugo AF.
europepmc   +1 more source

"I only knew how to search Google": students' reflections on a four-year information literacy curriculum. [PDF]

J Can Health Libr Assoc
Sanger S, Smith DA.
europepmc   +1 more source