Results 111 to 120 of about 1,469,506 (316)
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Specifying Reusable Components
Reusable software components need expressive specifications. This paper outlines a rigorous foundation to model-based contracts, a method to equip classes with strong contracts that support accurate design, implementation, and formal verification of ...
B. Meyer +8 more
core +3 more sources
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Efficiently Processing and Storing Library Linked Data using Apache Spark and Parquet [PDF]
Kumar Sharma, Ujjal Marjit, Utpal Biswas
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
How A Citizen Scientist Can Reuse & Link Biodiversity Heritage Library Data [PDF]
Siobhan Leachman
openalex +1 more source
A-posteriori provenance-enabled linking of publications and datasets via crowdsourcing
This paper aims to share with the digital library community different opportunities to leverage crowdsourcing for a-posteriori capturing of dataset citation graphs.
Berendt, Bettina +5 more
core
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
NAISC: An Authoritative Linked Data Interlinking Approach for the Library Domain [PDF]
Lucy McKenna +2 more
openalex +1 more source

