Results 221 to 230 of about 4,054,714 (369)

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

open access: yesChemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang   +8 more
wiley   +1 more source

Phytochemicals in Cancer Therapy: A Structured Review of Mechanisms, Challenges, and Progress in Personalized Treatment

open access: yesChemistry &Biodiversity, Accepted Article.
Objective: Cancer remains a global health challenge, necessitating new therapeutic options. Phytochemicals, with diverse chemical structures and biological activities, show promise as anticancer agents. This review explores key phytochemicals, their mechanisms, and their potential integration into cancer therapy.
Alaa A. A. Aljabali   +11 more
wiley   +1 more source

Exploring Chemical Variability in the Essential Oil of Artemisia absinthium L. in Relation to Different Phenological Stages and Geographical Location

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The plant essential oils (EOs) play a fundamental role in the adaptation to different habitats and environmental conditions. To verify the influence of these factors on the EO of Artemisia absinthium L., we conducted a pharmacognostic study on this species, collected during both the vegetative (V) and flowering (F) stages, in two different ...
Paola Malaspina   +5 more
wiley   +1 more source

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, EarlyView.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

A NLP analysis of digital demand for healthcare jobs in China. [PDF]

open access: yesSci Rep
Chen Y   +5 more
europepmc   +1 more source

Modified Oxymethylene Ethers Based on Technical Alcohol Mixtures and their Fuel Properties

open access: yesChemie Ingenieur Technik, Volume 97, Issue 5, Page 495-507, May 2025.
A modified oxymethylene ether (OME) synthesis based on C5 and C9 technical alcohol mixtures was developed. The produced compounds can be employed as neat fuel or as blending component for fossil or paraffinic diesel fuels. The modification of OME offers the possibility to adjust desired properties, enabling the evaluation of new application fields ...
Victor Zaghini Francesconi   +4 more
wiley   +1 more source

High‐Throughput and Automated Anion Transport Assays

open access: yesChemistry–Methods, EarlyView.
Synthetic ion transporters show promise as therapeutics, but assessing their activity can be time‐consuming, limiting the screening of large compound libraries. We developed an automated high‐throughput assay that determines 24 EC50 values in one day.
Kylie Yang   +7 more
wiley   +1 more source

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