Results 51 to 60 of about 6,725,926 (309)
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
Arranging the Pieces: A Survey of Library Practices Related to a Tabletop Game Collection
Evidence Based Library and Information Practice, 2017 Objective – The purpose of this study is to explore collection development, cataloguing, processing, and circulation practices for tabletop game collections in libraries. This study used the term “tabletop games” to refer to the array of game styles that
Teresa Slobuski +2 more
doaj +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Data literacy training needs of biomedical researchers
Journal of the Medical Library Association, 2016 Objective: The research investigated topic priorities for data literacy training for biomedical researchers and staff. Methods: An electronic survey was used to assess researchers’ level of knowledge related to data literacy skills and the relevance of ...
Lisa M. Federer +2 more
doaj
Developing text and data mining (TDM) support within a university research library
Insights: The UKSG JournalThe introduction of the text and data mining (TDM) exception in 2014 led to researchers asking for support from staff within Library Services at the University of Birmingham.
Lisa Bird, James Barnett
doaj +1 more source
A new model for accessible formats in the public library
The International Journal of Information, Diversity, & Inclusion, 2018 See .pdf file.
Kim Johnson, Sabina Iseli-Otto
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Journal of the Medical Library Association, 2018 Health sciences librarians from two institutions conducted an assessment of Covidence, a subscription-based systematic review tool, and Rayyan, a free competitor, for abilities, strengths, and limitations. Covidence mirrors the multiphase review process,
Liz Kellermeyer +2 more
doaj +1 more source
Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih +40 more
wiley +1 more source