In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Exploring the Origin of Molecular Chirality: A Standalone Suite of Tools to Visualize and Analyze Transition Current Density. [PDF]
Barlini A, Fusè M, Bloino J.
europepmc +1 more source
Understanding Operando Water Management in Hydroxide‐Exchange‐Membrane Fuel Cells
Effective water management is vital for high‐performance hydroxide‐exchange‐membrane fuel cells. Using a custom water‐flux station, this study quantifies how membrane thickness, microporous layers, and operating conditions dictate internal water transport.
Catherine M. Weiss +4 more
wiley +1 more source
Trust, Risk, and Uncertainty Surrounding the Use of AI in Health Care: Scoping Review of Studies on Public Perception. [PDF]
Godinho Nascimento H +5 more
europepmc +1 more source
Programming Actuation in 3D‐Printed Micro‐Architectures via Interfacial Adhesion Control
A two‐phase meniscus‐guided 3D printing method directly fabricates microscale poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) and poly(vinyl alcohol) (PVA) bilayers with in situ programmable interfaces. Modulating the meniscus stretching speed switches the interface between separated and bonded states, which controls the mechanical ...
Xiao Huan +13 more
wiley +1 more source
Bridging the theory-practice gap in laboratory medicine: development and application of a standardized case library for fostering clinical reasoning in postgraduate training. [PDF]
Wang Q +10 more
europepmc +1 more source
Angled Nozzle Aerosol Jet Printing to Streamline Conformal Patterning of Electronics
A modular, angled aerosol jet printhead is demonstrated to streamline patterning on nonplanar surfaces, including 90° step edges and confined internal geometries. A detailed analysis of gravitational settling for a sheathed aerosol flow and deconvolution of oblique deposition and gravitational effects supports the versatility of this approach for ...
Louis O. Morgan +4 more
wiley +1 more source
From episodes to populations: evolutionary explanation requires a constructive epistemology. [PDF]
Adler D.
europepmc +1 more source
A THz metasurface device integrating a metal–dielectric–metal resonator with microwall‐defined recessed regions enables spatially guided, label‐free sensing of micrometer‐scale plastic particles. The as‐fabricated devices exhibit distinct THz reflection resonances for 3.1‐µm polystyrene particles and a concentration‐dependent resonance‐frequency‐shift ...
Naoki Inomata +2 more
wiley +1 more source
STRIDE: A Sequencing Depth Robust Metric for Sparse Chromosome Conformation Capture Data Comparison. [PDF]
Xu B, Gao X, Tao W, Zhang Z, Li F.
europepmc +1 more source

