Results 51 to 60 of about 304,360 (262)

Splittable Lie Groups and Lie Algebras

Journal of Algebra, 2000
Let us call a finite-dimensional Lie algebra \(\mathfrak g\) over a field of characteristic zero Malcev splittable if \(\operatorname {ad}{\mathfrak g}\) is splittable in the sense that for each element of \(\operatorname {ad}{\mathfrak g}\) the semisimple and nilpotent Jordan component belong to \(\operatorname {ad}{\mathfrak g}\).
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Minimal Matrix Representations of Decomposable Lie Algebras of Dimension Less Than or Equal to Five

Extracta Mathematicae, 2018
We obtain minimal dimension matrix representations for each decomposable five-dimensional Lie algebra over R and justify in each case that they are minimal.
Ryad Ghanam, Manoj Lamichhane, Gerard Thompson   +2 more
doaj  

Reduction of Dynamics with Lie Group Analysis

Advances in Mathematical Physics, 2012
This paper is mainly a review concerning singular perturbation methods by means of Lie group analysis which has been presented by the author. We make use of a particular type of approximate Lie symmetries in those methods in order to construct reduced ...
M. Iwasa
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Controllability of affine right-invariant systems on solvable Lie groups [PDF]

Discrete Mathematics & Theoretical Computer Science, 1997
The aim of this paper is to present some recent results on controllability of right-invariant systems on Lie groups. From the Lie-theoretical point of view, we study conditions under which subsemigroups generated by half-planes in the Lie algebra of a ...
Yuri L. Sachkov
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Clinical Manifestations and Management of Primary Ciliary Dyskinesia in ENT Practice

B-ENT
Primary ciliary dyskinesia (PCD) comprises a wide range of phenotypes related to the impaired function of epithelial cilia. Histologically altered or absent cilia lead to multiple and variable consequences at the clinical level.
Lionel Benchimol, Simon Dubois, Noemie Bricmont, Romane Bonhiver, Marie-Christine Seghaye, Philippe P. Lefebvre, Jean-François Papon, Céline Kempeneers, Anne-Lise Poirrier   +8 more
doaj   +2 more sources

Reduction of Symplectic Lie Algebroids by a Lie Subalgebroid and a Symmetry Lie Group

Symmetry, Integrability and Geometry: Methods and Applications, 2007
We describe the reduction procedure for a symplectic Lie algebroid by a Lie subalgebroid and a symmetry Lie group. Moreover, given an invariant Hamiltonian function we obtain the corresponding reduced Hamiltonian dynamics. Several examples illustrate the
David Iglesias, Juan Carlos Marrero, David Martín de Diego, Eduardo Martínez, Edith Padrón   +4 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source