Results 31 to 40 of about 224,740 (268)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Homogeneous Triebel-Lizorkin Spaces on Stratified Lie Groups
Homogeneous Triebel-Lizorkin spaces with full range of parameters are introduced on stratified Lie groups in terms of Littlewood-Paley-type decomposition.
Guorong Hu
doaj +1 more source
Compact Lie Groups, Generalised Euler Angles, and Applications
This is mainly a review of an intense 15-year long collaboration between the authors on explicit realisations of compact Lie groups and their applications.
Sergio Luigi Cacciatori, Antonio Scotti
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Lie Group Methods in Blind Signal Processing
This paper deals with the use of Lie group methods to solve optimization problems in blind signal processing (BSP), including Independent Component Analysis (ICA) and Independent Subspace Analysis (ISA). The paper presents the theoretical fundamentals of
Dariusz Mika, Jerzy Jozwik
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
On the Structure of Lie Pseudo-Groups
We compare and contrast two approaches to the structure theory for Lie pseudo-groups, the first due to Cartan, and the second due to the first two authors.
Peter J. Olver +2 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source

