Results 41 to 50 of about 6,154,040 (243)
Random Action of Compact Lie Groups and Minimax Estimation of a Mean Pattern [PDF]
, 2011 This paper considers the problem of estimating a mean pattern in the setting of Grenander's pattern theory. Shape variability in a dataset of curves or images is modeled by the random action of elements in a compact Lie group on an infinite dimensional ...
Gadat, Sébastien +3 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Integrating Hamiltonian systems defined on the Lie groups SO(4) and SO(1,3) [PDF]
, 2007 In this paper we study constrained optimal control problems on semi-simple Lie groups. These constrained optimal control problems include Riemannian, sub-Riemannian, elastic and mechanical problems. We begin by lifting these problems, through the Maximum
Biggs, James, Holderbaum, William
core +1 more source
Braided Lie bialgebras associated to Kac-Moody algebras [PDF]
, 2008 Braided-Lie bialgebras have been introduced by Majid, as the Lie versions of Hopf algebras in braided categories. In this paper we extend previous work of Majid and of ours to show that there is a braided-Lie bialgebra associated to each inclusion of Kac-
Grabowski, Jan
core +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Jacobson topology of Prim* L¹(G) for exponential Lie groups [PDF]
, 2007 Ungermann O. The Jacobson topology of Prim* L¹(G) for exponential Lie groups.
Ungermann, Oliver
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source