Results 61 to 70 of about 293,903 (262)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

QUELLE DIE SINGT [PDF]

open access: yesHum, 2009
Es ist die Rede von einer durch die Schönheit der Heimatslandschaft motivierenden Poesie wie überhaupt die Schönheit des Kosmos betreffend oder der Natur im Ganzen, in der „Logos, und nicht Kaos“ herrscht.
Šimun Musa
doaj  

Mignon / von F. Liszt [PDF]

open access: yes, 2011
Mignon's Lied ; Mignons Lied R 592 für Mezzo-Sopran. Dichtung von v. Goethe.
Goethe, Johann Wolfgang von   +1 more
core  

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

A Fall Fringe Festival, Seven Deadly Sins [PDF]

open access: yes, 1998
This is the concert program of the Fall Fringe Festival, Seven Deadly Sins performance on Friday - Sunday, November 6 - 8, 1998 at 7:00 p.m. and Sunday, November 8, 1998 at 3:00 p.m., at Studio 210, Boston University Theater, 263 Huntington Avenue ...
School of Music, Boston University
core  

Dialectal variation in german 3-verb clusters : a surface-oriented optimality theoretic account [PDF]

open access: yes, 2004
We present data from an empirical investigation on the dialectal variation in the syntax of German 3-verb clusters, consisting of a temporal auxiliary, a modal verb, and a predicative verb. The ordering possibilities vary greatly among the dialects. Some
Schmid, Tanja, Vogel, Ralf
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Las rimas de Gustavo Adolfo Bécquer (Sevilla, 1836 – Madrid, 1870) en la canción lírica: una revisión bibliográfica

open access: yesMúsica Oral del Sur, 2019
El presente artículo gira en torno a la musicalización de las rimas de G. A. Bécquer en el género de la canción lírica, fenómeno desarrollado desde el último tercio del siglo XIX hasta nuestros días.
Candela Tormo Valpuesta
doaj  

Epistemic Sentimentalism and Epistemic Reason-Responsiveness [PDF]

open access: yes, 2018
Epistemic Sentimentalism is the view that emotional experiences such as fear and guilt are a source of immediate justification for evaluative beliefs. For example, guilt can sometimes immediately justify a subject’s belief that they have done something ...
Cowan, Robert
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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