Results 21 to 30 of about 11,856,235 (233)

MEMORAMDUM, INTEGRATION ET LIEN SOCIAL AU CAMEROUN [PDF]

Ziglôbitha
Résumé : La recherche de l’harmonie sociale entre les communautés linguistiques a conduit le Cameroun à adopter la politique linguistique du bilinguisme français et anglais, comme langues d’intégration des différents groupes ethnolinguistiques dans la ...
Laure Sandrine TSAKOU
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

LIEN SOCIAL ET AUTORITÉ. Regards éthico-politique et économique sur la (post)modernité

, 2020
editorial reviewedet ouvrage propose une réflexion sur le lien social, le statut de l'individu et de l'autorité dans les sociétés pré-modernes et postmodernes.
Somabe, Kokou Kouzouahin, SOMABE,
core   +1 more source

LE LIEN SOCIAL AU MAROC : QUEL AVENIR ?

Revue Economie, Gestion et Société, 2018
Since independence, Moroccan society has been undergoing profound changes in the value system and attitudes towards domestic and family life. These processes of change, influenced by new technological tools and globalization, have led to the emergence of
Asmaa MABROUK, Leila SKALLI
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Diseños del orden social en testamentos de indios de Córdoba del Tucumán (1573-1650)

Nuevo mundo - Mundos Nuevos, 2017
Dans cette étude, nous analysons un ensemble de testaments d'indigènes. Ceux-ci sont dictés dans la juridiction de Cordoba (gouvernement de Tucumán) sur une période comprise entre 1573 et 1650.
Beatriz Bixio
doaj   +1 more source

Qui doit nourrir l'enfant dont le père est absent ? Le cas de la Belgique

, 1997
L'article s'inscrit dans le dossier thématique "Politiques du père" de la revue Lien social et politique - RIAC. L'auteur présente un aperçu de la manière dont se pose, en Belgique, la question « Qui doit nourrir l'enfant dont le père est absent ?
Paye, Olivier
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source