Results 61 to 70 of about 10,179,200 (235)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Improving cardiovascular health in black men through a 24-week community-based team lifestyle change intervention: The black impact pilot study

American Journal of Preventive Cardiology, 2022
Background: Higher cardiovascular health scores, using American Heart Association's (AHA) Life's Simple 7 (LS7), have been associated with lower risk of cardiovascular disease, type 2 diabetes, cancer, and mortality among all racial/ethnic groups ...
Joshua J. Joseph, Timiya S. Nolan, Amaris Williams, Alicia McKoy, Songzhu Zhao, Emmanuela Aboagye-Mensah, Bjorn Kluwe, James B. Odei, Guy Brock, Dana Lavender, John Gregory, Darrell M. Gray, II   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cardiovascular Health and Healthcare Utilization and Expenditures Among Medicare Beneficiaries: The REasons for Geographic And Racial Differences in Stroke (REGARDS) Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundBetter cardiovascular health is associated with lower cardiovascular disease risk. Methods and ResultsWe determined the association between cardiovascular health and healthcare utilization and expenditures in the REasons for Geographic And ...
Kristal J. Aaron, Lisandro D. Colantonio, Luqin Deng, Suzanne E. Judd, Julie L. Locher, Monika M. Safford, Mary Cushman, Meredith L. Kilgore, David J. Becker, Paul Muntner   +9 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Greater Adherence to Life's Simple 7 Is Associated With Less Arterial Stiffness: the Atherosclerosis Risk in Communities (ARIC) Study [PDF]

, 2019
BACKGROUND: Greater arterial stiffness is associated independently with increased cardiovascular disease risk. The American Heart Association (AHA) has recommended following "Life's Simple 7 (LS7)" to optimize cardiovascular health; we tested whether ...
Cheng, Susan, Folsom, Aaron R, Meyer, Michelle L, Oyenuga, Abayomi O, Tanaka, Hirofumi   +4 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Cardiovascular Health Status, Migraine Risk, and Mortality Outcomes in Migraine Individuals: Insights From NHANES

Brain and Behavior
Objectives The study analyzes the link between cardiovascular health, measured through the Life's Simple 7 (LS7) score, and the potential risk of migraines. Moreover, the research delves into the possibility that better cardiovascular health might lessen
Hongwei Liu, Wenzhi Niu, Gaiying Ma, Haixia Fan, Minheng Zhang, Yu Wang, Mingni Yang   +6 more
doaj   +1 more source

The American Heart Association Life's Simple 7 and incident cognitive impairment: The REasons for Geographic And Racial Differences in Stroke (REGARDS) study

, 2014
BACKGROUND: Life's Simple 7 is a new metric based on modifiable health behaviors and factors that the American Heart Association uses to promote improvements to cardiovascular health (CVH).
Thacker, Evan L., Unverzagt, Frederick W., Gillett, Sarah R., Wadley, Virginia G., Judd, Suzanne E., McClure, Leslie A., Cushman, Mary, Howard, Virginia J.   +7 more
core   +1 more source