Results 111 to 120 of about 10,012,980 (241)

Lowering the risk of hyperuricemia and gout is associated with ideal cardiovascular health

Journal of Health, Population and Nutrition
Background Hyperuricemia (HUA) and gout have been demonstrated as independent risk factors for cardiovascular disease. The relationship between the recently updated Life’s Essentials 8 (LE8), which measures ideal cardiovascular health (CVH), and HUA and ...
Pengfei Liu, Kaisaierjiang Kadier, Chunying Cui, Xinliang Peng, Wenqing Hou, Aikeliyaer Ainiwaer, Asiya Abudesimu, Qi Wang, Mierxiati Ainiwan, Xiaozhu Liu, Yitong Ma, Xiang Ma   +11 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Association of cardiovascular health with morbidity and mortality among U.S. adults with osteoarthritis: a population-based study

BMC Public Health
Background Osteoarthritis (OA) is recognized as the most common joint disease with serious public health implications. Cardiovascular health (CVH) is also an issue that is frequently emphasized in public health and has an impact on a variety of diseases ...
Xuan Zhang, Haoxian Tang, Jingtao Huang, Hanyuan Lin, Qinglong Yang, Nan Luo, Jian Weng, Hui Zeng, Fei Yu   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Association of new Life’s Essential 8 with biological aging among the national health and nutrition examination surveys

Scientific Reports
The Life’s Essential 8 (LE8) score was updated by the American Heart Association, which constituted cardiovascular health (CVH) and was significantly associated with overall and cardiovascular disease-specific mortality.
Xiaoli Chen, Xin Yin, Xin Chen, Yajie Gao, Nan Ye, Xingkang He   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Association Between Life’s Essential 8 and Frailty in Adults with Asthma

Dose-Response
Objectives To investigate the correlation between Life’s Essential 8 (LE8) and frailty in adults with asthma using data from National Health and Nutrition Examination Survey (NHANES). Methods We conducted a cross-sectional study by NHANES data (2001-2018)
Jiao Xu, Min Zhang
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Association between life’s essential 8 and metabolic dysfunction-associated steatotic liver disease among US adults

Background Metabolic dysfunction-associated steatotic liver disease(MASLD) is the most common cause of chronic liver disease. Clinical evidences have demonstrated the link between MASLD and the increased risk of cardiovascular disease (CVD) development ...
Yixuan Ding, Prof Fei Li, Zheng Wang, Fei Li, Bohan Huang, Feng Cao   +5 more
core   +1 more source

Higher Life’s Essential 8 score is associated with lower risk of kidney stones in Chinese adults: a cross-sectional study

BMC Public Health
Background Kidney stones are widely prevalent throughout the world and impose a significant economic and medical burden on individuals and society. The aim of this study was to analyze the association between Life’s Essential 8 (LE8) score and kidney ...
Xinqiang Chen, Yanjiao Wang, Fei Mi, Junmin Zhou, Xuehui Zhang, Zixiu Qin, Jia Zeng, Chuanwen Fu, Ying Qian, Jizhuo Yang, Baima Kangzhuo, Yan Tan, Jinjie Xia, Qiong Meng, Yuemei Feng, Jianzhong Yin   +15 more
doaj   +1 more source