Results 61 to 70 of about 10,012,980 (241)

Association between Life’s Essential 8 and Cerebral Small Vessel Disease

Stroke and Vascular Neurology
Background Given that associations of Life’s Essential 8 (LE8) and cerebral small vessel disease (CSVD) or its imaging markers were unclear, we examined relationship between them.Methods The cross-sectional study included community residents from the ...
Yongjun Wang, Yilong Wang, Jing Jing, Xia Meng, Shan Li, Yuesong Pan, Yun Chen, Xueli Cai, Tiemin Wei, Suying Wang, Lerong Mei, Yingying Yang, Mengxing Wang, Dandan Liu   +13 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Association of lung health and cardiovascular health (Life’s Essential 8)

Frontiers in Medicine
BackgroundCardiorespiratory health issues often intersect. This study explored the relationship between lung health and the recently updated Cardiovascular Health Measure (Life’s Essential 8).MethodsData from the 2007–2018 National Health and Nutrition ...
Wanjia Zhang, Menglong Zou, Junyao Liang, Dexu Zhang, Man Zhou, Hui Feng, Chusen Tang, Jie Xiao, Zhan Yi, Yin Xu   +9 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Abstract P189: Sexual Minority Status Disparities in Life’s Simple 7 and Life’s Essential 8 Cardiovascular Health Scores, a French Nationwide Population-Based Study

, 2023
International audienceA higher burden of cardiovascular disease risk factors has been reported in sexual minority populations (SM), such as lesbian, gay, bisexual, and non-heterosexual, compared to heterosexual populations.
Beach, Lauren, Jean-Philippe Empana, Carl G Streed, Caceres, Billy, Goldberg, Marcel, Billy A Caceres, Xavier Jouven, Empana, Jean-Philippe, Mathilde Touvier, Jouven, Xavier, Touvier, Mathilde, Lauren B Beach, Streed, Carl, Marcel Goldberg, Omar Deraz, Deraz, Omar, Marie Zins, Zins, Marie   +17 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Association between life’s essential 8 and periodontitis: a study based on NHANES 2009–2014 [PDF]

BackgroundThis research aims to investigate the relationship between Life’s Essentials 8 (LE8), the American Heart Association’s latest indicator, and periodontitis.
KeGui Hou, Shi Li, JiaRui Liu, Hongli Zhang, Wenpeng Song, Zhaofeng Ma   +5 more
core   +1 more source

Impact of the American Heart Association’s Life’s Essential 8 goals on incident cardiovascular diseases (CVD) in the Strong Heart Family Study [PDF]

, 2023
Thesis (Master's)--University of Washington, 2023Background: Cardiovascular diseases (CVD) are a leading cause of morbidity and mortality among American Indians.
Yadanar Paing, Pyone
core   +2 more sources