Results 61 to 70 of about 901,616 (214)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Corps embryoïdes : biologie moléculaire et cellules vivantes

open access: yesAteliers d'Anthropologie, 2019
The ethnography of a basic research technique in developmental biology—the production of embryoid bodies (EB)—shows how cells are the work materials for a scientific approach that is based on a molecular conception of life, and connects different species.
Noémie Merleau-Ponty
doaj   +1 more source

COLORFUL LIFE HEALTHY LIFE

open access: yesInternational Journal of Research -GRANTHAALAYAH, 2014
The information provided in this article is to obtain a further understanding of the beneficial health effects of various food pigments naturally occurring in plant products. The bright colors of many vegetables contribute much to their appeal. The colors result from the various pigments contained in their tissues.
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

«Heightened sense of life...»: A.T. Tvardovsky and I.A. Bunin about eternal problems of existence

open access: yesPolylinguality and Transcultural Practices, 2011
The article discusses specific points of view of A.T. Tvardovsky and I.A. Bunin on matters of life and death, analyzes the main aspects of their world outlook, which unites them in understanding the meaning of human existence.
S R Tumanova
doaj  

Wartość własnej śmierci [The value of one’s own death] [PDF]

open access: yesAnaliza i Egzystencja, 2015
In the article I defend the view that nobody can appraise the value of his own death.
Mirosław Rutkowski
doaj  

Features of the Interior Environment of the Dwellings of the Peoples of the Middle Volga Region at the End of the XIX – the First Half of the XX Centuries

open access: yesЭтническая культура, 2020
The article pays attention to the interior environment of the dwellings of the Middle Volga region at the end of the 19th – first half of the 20th centuries, which due to ethnonational and historical and cultural factors, may have some specific features.
Vladimir A. Krasnoshchyokov
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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